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基于格兰杰因果关系的非线性连接。

Nonlinear connectivity by Granger causality.

机构信息

Laboratory of Neurophysics and Physiology, CNRS UMR 8119, Université Paris Descartes, Paris, France.

出版信息

Neuroimage. 2011 Sep 15;58(2):330-8. doi: 10.1016/j.neuroimage.2010.01.099. Epub 2010 Feb 2.


DOI:10.1016/j.neuroimage.2010.01.099
PMID:20132895
Abstract

The communication among neuronal populations, reflected by transient synchronous activity, is the mechanism underlying the information processing in the brain. Although it is widely assumed that the interactions among those populations (i.e. functional connectivity) are highly nonlinear, the amount of nonlinear information transmission and its functional roles are not clear. The state of the art to understand the communication between brain systems are dynamic causal modeling (DCM) and Granger causality. While DCM models nonlinear couplings, Granger causality, which constitutes a major tool to reveal effective connectivity, and is widely used to analyze EEG/MEG data as well as fMRI signals, is usually applied in its linear version. In order to capture nonlinear interactions between even short and noisy time series, a few approaches have been proposed. We review them and focus on a recently proposed flexible approach has been recently proposed, consisting in the kernel version of Granger causality. We show the application of the proposed approach on EEG signals and fMRI data.

摘要

神经元群体之间的通讯,反映在短暂的同步活动中,是大脑中信息处理的机制。尽管人们普遍认为这些群体之间的相互作用(即功能连接)具有高度的非线性,但非线性信息传递的数量及其功能作用尚不清楚。了解脑系统之间通信的最新方法是动态因果建模 (DCM) 和格兰杰因果关系。虽然 DCM 模型是非线性耦合,但格兰杰因果关系构成了揭示有效连接的主要工具,并且广泛用于分析 EEG/MEG 数据以及 fMRI 信号,但通常以其线性版本应用。为了捕捉即使是短而嘈杂的时间序列之间的非线性相互作用,已经提出了几种方法。我们将对它们进行回顾,并重点介绍最近提出的一种灵活的方法,该方法由格兰杰因果关系的核版本组成。我们展示了该方法在 EEG 信号和 fMRI 数据上的应用。

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