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EXTra hit for mouse osteochondroma.

作者信息

Bovée Judith V M G

机构信息

Department of Pathology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

出版信息

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1813-4. doi: 10.1073/pnas.0914431107.

DOI:10.1073/pnas.0914431107
PMID:20133829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2836704/
Abstract
摘要

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本文引用的文献

1
A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes.软骨细胞中克隆失活 Ext1 导致的骨软骨瘤发生的小鼠模型。
Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2054-9. doi: 10.1073/pnas.0910875107. Epub 2009 Dec 22.
2
Targeting EXT1 reveals a crucial role for heparan sulfate in the growth of multiple myeloma.靶向 EXT1 揭示了肝素硫酸在多发性骨髓瘤生长中的关键作用。
Blood. 2010 Jan 21;115(3):601-4. doi: 10.1182/blood-2009-02-204396. Epub 2009 Nov 13.
3
Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher.ext2/dackel和papst1/pinscher对斑马鱼骨骼生成的调控
PLoS Genet. 2008 Jul 25;4(7):e1000136. doi: 10.1371/journal.pgen.1000136.
4
The role of EXT1 in nonhereditary osteochondroma: identification of homozygous deletions.EXT1在非遗传性骨软骨瘤中的作用：纯合缺失的鉴定。
J Natl Cancer Inst. 2007 Mar 7;99(5):396-406. doi: 10.1093/jnci/djk067.
5
Fibrous dysplasia as a stem cell disease.骨纤维异常增殖症作为一种干细胞疾病。
J Bone Miner Res. 2006 Dec;21 Suppl 2:P125-31. doi: 10.1359/jbmr.06s224.
6
Mice deficient in Ext2 lack heparan sulfate and develop exostoses.Ext2基因缺陷的小鼠缺乏硫酸乙酰肝素，并会出现外生骨疣。
Development. 2005 Nov;132(22):5055-68. doi: 10.1242/dev.02088. Epub 2005 Oct 19.
7
Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification.依赖于Ext1的硫酸乙酰肝素在软骨内骨化过程中调节Ihh信号传导的范围。
Dev Cell. 2004 Jun;6(6):801-13. doi: 10.1016/j.devcel.2004.05.009.
8
Reevaluation of a genetic model for the development of exostosis in hereditary multiple exostosis.遗传性多发性外生骨疣中外生骨疣发育遗传模型的重新评估。
Am J Med Genet. 2002 Sep 15;112(1):1-5. doi: 10.1002/ajmg.10635.
9
EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.散发性和遗传性骨软骨瘤及继发性软骨肉瘤中的EXT基因突变分析与杂合性缺失
Am J Hum Genet. 1999 Sep;65(3):689-98. doi: 10.1086/302532.
10
The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate.假定的肿瘤抑制因子EXT1可改变细胞表面硫酸乙酰肝素的表达。
Nat Genet. 1998 Jun;19(2):158-61. doi: 10.1038/514.