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An in vivo demonstration of functional G protein-coupled receptor dimers.

作者信息

Vassart Gilbert

机构信息

Faculty of Medicine, Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Free University of Brussels, 808 route Lennik, B-1070 Brussels, Belgium.

出版信息

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1819-20. doi: 10.1073/pnas.0914432107. Epub 2010 Feb 1.

Abstract
摘要

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本文引用的文献

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2
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.
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The apparent cooperativity of some GPCRs does not necessarily imply dimerization.
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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.
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