St. Jude Children's Research Hospital, 262 DannyThomas Place, Memphis, TN 38105-3678, USA.
Am J Trop Med Hyg. 2010 Feb;82(2):324-9. doi: 10.4269/ajtmh.2010.09-0365.
Clinical observations and some studies suggest that dengue virus infection is more severe among children with better nutritional status. We examined the nutritional status of children in El Salvador and its relationship between this and the severity of dengue infection. Z-scores for weight-for-age, height-for-age, and body mass index (BMI)-for-age of children with dengue fever (66), dengue hemorrhagic fever (62), and healthy controls (74) were compared. There were no differences in weight-for-age or BMI-for-age Z-scores between the three groups. Children with dengue fever had a greater height-for-age than healthy controls but no significant differences in rates of stunting. There was no difference in height between children with dengue fever and dengue hemorrhagic fever. Excess nutrition does not appear to be a risk factor for severe forms of dengue infection in El Salvador, nor does malnutrition appear to be predictive of good outcomes.
临床观察和一些研究表明，营养状况较好的儿童感染登革热病毒后病情更为严重。我们研究了萨尔瓦多儿童的营养状况及其与登革热感染严重程度的关系。比较了登革热（66 例）、登革出血热（62 例）和健康对照（74 例）患儿的体重-年龄 Z 评分、身高-年龄 Z 评分和体重指数（BMI）-年龄 Z 评分。三组间体重-年龄 Z 评分或 BMI-年龄 Z 评分无差异。登革热患儿的身高-年龄 Z 评分大于健康对照组，但生长迟缓率无显著差异。登革热和登革出血热患儿的身高无差异。在萨尔瓦多，营养过剩似乎不是登革热严重感染的危险因素，营养不良也似乎不能预测良好的预后。
