Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Chin Med J (Engl). 2010 Jan 20;123(2):203-7.
Measurement of anterior segment parameters plays an important role in diagnosis and treatment of glaucoma. The objective of this study was to evaluate the repeatability and reproducibility of anterior chamber volume (ACV) measurements with rotating scheimpflug camera (RSC) and to examine agreement with anterior segment optical coherence tomography (AS-OCT).
Thirty nine healthy normal subjects were recruited from the Eye Center of Tongren Hospital. ACV was measured using RSC and AS-OCT in a randomly selected eye for each subject. For RSC measurements, both automatic and manual ACV measurements and 2 independent operators' ACV measurements were obtained. All subjects were invited for 3 visits within a week to evaluate repeatability and reproducibility of ACV measurement by RSC. Agreement was evaluated between RSC and AS-OCT.
Good repeatability and reproducibility were found for both automatic and manual ACV measurements obtained by RSC. For intrasession repeatability, coefficient of variation (CVw) and intraclass correlation coefficient (ICC) values for automatic were 3.52% and 0.98; the values for manual were 3.44% and 0.97, respectively. For intersession reproducibility, the respective CVw and ICC values were 3.96% and 0.96. Good agreement was also found in 2 operators for both automatic and manual ACV measurements; nevertheless, poor agreement was found between RSC and AS-OCT (95% confidence interval (CI) for agreement of automatic RSC measurement versus AS-OCT were -96.3 to 72.8 microl and 95% CI for agreement of manual RSC measurement versus AS-OCT were between -41.7 to 10.1 microl).
Both RSC automatic and manual ACV measurements showed good repeatability and reproducibility, and showed comparable agreement between 2 independent operators, but poor agreement was found between RSC and AS-OCT.
眼前节参数的测量在青光眼的诊断和治疗中起着重要作用。本研究的目的是评估旋转式Scheimpflug 相机（RSC）测量前房容积（ACV）的可重复性和再现性，并检查与眼前节光学相干断层扫描（AS-OCT）的一致性。
从同仁医院眼科中心招募了 39 名健康正常受试者。为每个受试者随机选择一只眼，使用 RSC 和 AS-OCT 测量 ACV。对于 RSC 测量，获得了自动和手动 ACV 测量以及 2 位独立操作者的 ACV 测量。所有受试者在一周内接受 3 次访问，以评估 RSC 测量的 ACV 重复性和再现性。评估了 RSC 和 AS-OCT 之间的一致性。
RSC 获得的自动和手动 ACV 测量均具有良好的可重复性和再现性。对于日内重复性，自动测量的变异系数（CVw）和组内相关系数（ICC）值分别为 3.52%和 0.98；手动测量的分别为 3.44%和 0.97。对于日间可重复性，相应的 CVw 和 ICC 值分别为 3.96%和 0.96。对于自动和手动 ACV 测量，两位操作者之间也有很好的一致性；然而，RSC 和 AS-OCT 之间的一致性较差（自动 RSC 测量与 AS-OCT 之间一致性的 95%置信区间（CI）为-96.3 至 72.8 微升，手动 RSC 测量与 AS-OCT 之间一致性的 95%CI 为-41.7 至 10.1 微升）。
RSC 自动和手动 ACV 测量均具有良好的重复性和再现性，并且在 2 位独立操作者之间具有可比性，但 RSC 和 AS-OCT 之间的一致性较差。
