Pentacam 与眼前节光学相干断层扫描仪测量眼前节的对比研究。

Comparative study of anterior segment measurement with Pentacam and anterior segment optical coherence tomography.

机构信息

Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Ophthalmology and Visual Science Key Laboratory, Beijing, China.

出版信息

Can J Ophthalmol. 2010 Dec;45(6):627-31. doi: 10.3129/i10-068.

DOI:10.3129/i10-068

PMID:21135897

Abstract

OBJECTIVE

To evaluate the repeatability of central corneal thickness (CCT), anterior chamber volume (ACV), and central anterior chamber depth (CACD) measurements obtained using a Pentacam rotating Scheimpflug camera, and to examine their agreement with measurements obtained using an anterior segment optical coherence tomography (AS-OCT) imaging system.

DESIGN

Observational cross-sectional study.

PARTICIPANTS

Fifty eyes from 50 healthy subjects were recruited.

METHODS

CCT, CACD, and ACV were measured. Subjects were re-examined twice within a week of the first measurements. Intrasession and intersession within-subject SD (Sw), precision (1.96 × Sw), coefficient of variation (CVw: 100 × Sw / overall mean), and intraclass correlation coefficient (ICC) were calculated to evaluate repeatability and reproducibility. Bland-Altman plots were used to assess agreements between Pentacam and AS-OCT measurements.

RESULTS

For intrasession repeatability, CVw and ICC values were 0.78 and 0.98 for CCT, 0.92 and 0.99 for CACD, and 3.52 and 0.98 for ACV, respectively. For intersession repeatability, CVw and ICC values were 1.19 and 0.96 for CCT, 1.25 and 0.99 for CACD, and 3.96 and 0.96 for ACV, respectively. The AS-OCT CCT measurement (519.23 [SD 34.37] µm) was 18.53 µm less than the Pentacam measurement (537.76 [SD 31.84] µm). The Pentacam CACD measurement (3.03 [SD 0.32] mm) was 0.08 less than the AS-OCT measurement (3.11 [SD 0.31] mm). The Pentacam ACV measurement (165.56 [SD 34.86] µL) was 14.21 µL less than the AS-OCT measurement (179.77 [SD 34.57] µL).

CONCLUSIONS

Although the Pentacam measurements of the anterior segment parameters were reliable, their agreement with the AS-OCT measurements was not sufficient.

摘要

目的

评估 Pentacam 旋转 Scheimpflug 相机测量中央角膜厚度（CCT）、前房容积（ACV）和中央前房深度（CACD）的重复性，并比较其与眼前节光学相干断层扫描（AS-OCT）成像系统测量值的一致性。

设计

观察性横断面研究。

参与者

招募了 50 名健康受试者的 50 只眼。

方法

测量 CCT、CACD 和 ACV。受试者在首次测量后一周内接受了两次复查。计算了各次测量的内组内标准差（Sw）、精密度（1.96×Sw）、变异系数（CVw：100×Sw/总平均值）和组内相关系数（ICC），以评估重复性和再现性。使用 Bland-Altman 图评估 Pentacam 和 AS-OCT 测量值之间的一致性。

结果

在日内重复性方面，CCT 的 CVw 和 ICC 值分别为 0.78 和 0.98，CACD 为 0.92 和 0.99，ACV 为 3.52 和 0.98。在日间重复性方面，CCT 的 CVw 和 ICC 值分别为 1.19 和 0.96，CACD 为 1.25 和 0.99，ACV 为 3.96 和 0.96。AS-OCT 的 CCT 测量值（519.23[标准差 34.37]µm）比 Pentacam 测量值（537.76[标准差 31.84]µm）小 18.53µm。Pentacam 的 CACD 测量值（3.03[标准差 0.32]mm）比 AS-OCT 测量值（3.11[标准差 0.31]mm）小 0.08mm。Pentacam 的 ACV 测量值（165.56[标准差 34.86]µL）比 AS-OCT 测量值（179.77[标准差 34.57]µL）小 14.21µL。