Mineura K, Sasajima T, Kowada M, Uesaka Y, Shishido F
Neurosurgical Service, Akita University Hospital, Japan.
J Nucl Med. 1991 Apr;32(4):726-8.
A case of gliomatosis cerebri was studied with positron emission tomography (PET). Carbon-11-L-methionine (11C-Met) accumulated in the diffusely infiltrative tumorous area more widely and accurately than the lesion detected by conventional x-ray computerized tomography (CT) or magnetic resonance (MR) imaging. Autopsy findings three months after the time of the PET study showed good anatomical correspondence between the extent of densely aggregated tumor cells and the region with high uptake of 11C-Met. PET may offer an innovative approach in the delineation of gliomatosis cerebri, which has not been clearly recognized by CT or MR.
对一例大脑胶质瘤病患者进行了正电子发射断层扫描（PET）研究。与传统X线计算机断层扫描（CT）或磁共振（MR）成像所检测到的病变相比，碳-11-L-蛋氨酸（11C-Met）在弥漫性浸润性肿瘤区域的聚集更为广泛和准确。PET研究三个月后的尸检结果显示，密集聚集的肿瘤细胞范围与11C-Met高摄取区域之间在解剖学上具有良好的对应关系。PET可能为大脑胶质瘤病的界定提供一种创新方法，而CT或MR尚未明确识别出该疾病。
