Department of Paediatric Neurology and Developmental Medicine, Dr. von Haunersches Children's Hospital, University of Munich, Germany.
Eur J Paediatr Neurol. 2010 Nov;14(6):496-502. doi: 10.1016/j.ejpn.2010.01.002. Epub 2010 Feb 6.
Task-specific body-weight-supported treadmill therapy improves walking performance in children with central gait impairment. The aim of the study was to investigate the effect of robotic-assisted treadmill therapy on standing and walking performance in children and adolescents with cerebral palsy and to determine parameters influencing outcome.
20 Patients (mean age 11.0 ± 5.1, 10 males and 10 females) with cerebral palsy underwent 12 sessions of robotic-assisted treadmill therapy using the driven gait orthosis Lokomat. Outcome measures were the dimensions D (standing) and E (walking) of the Gross Motor Function Measure (GMFM).
Significant improvements in dimension D by 5.9% (± 5.2, p=0.001) and dimension E by 5.3% (± 5.6, p<0.001) of the GMFM were achieved. Improvements in the GMFM D and E were significantly greater in the mildly affected cohort (GMFCS I and II) compared to the more severely affected cohort (GMFCS III and IV). Improvement of the dimension E but not of D correlated positively with the total distance and time walked during the trial (r(s)=0.748, p<0.001).
Children and adolescents with bilateral spastic cerebral palsy showed improvements in the functional tasks of standing and walking after a 3-week trial of robotic-assisted treadmill therapy. The severity of motor impairment affects the amount of the achieved improvement.
特定任务的体重支撑跑步机疗法可改善中枢性步态障碍儿童的步行表现。本研究旨在探讨机器人辅助跑步机疗法对脑瘫儿童站立和行走表现的影响，并确定影响疗效的参数。
20 名脑瘫患儿（平均年龄 11.0±5.1 岁，男 10 名，女 10 名）接受了 12 次机器人辅助跑步机治疗，使用驱动步态矫形器 Lokomat。疗效评估指标为粗大运动功能测量（GMFM）的 D（站立）和 E（行走）维度。
GMFM 的 D 维度（站立）显著改善 5.9%（±5.2，p=0.001），E 维度（行走）显著改善 5.3%（±5.6，p<0.001）。GMFCS I 和 II 轻度脑瘫患儿的 GMFM D 和 E 改善程度显著大于 GMFCS III 和 IV 重度脑瘫患儿。E 维度的改善（但不是 D 维度）与试验期间的总步行距离和时间呈正相关（r(s)=0.748，p<0.001）。
经过 3 周的机器人辅助跑步机治疗后，双侧痉挛性脑瘫儿童在站立和行走的功能任务上都有改善。运动障碍的严重程度影响着所取得的改善程度。
