Division of Child and Adolescent Psychiatry, Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Korea.
Psychiatry Investig. 2009 Dec;6(4):278-85. doi: 10.4306/pi.2009.6.4.278. Epub 2009 Nov 5.
The objective of this study was to examine the effect of perinatal and familial risk factors on full syndrome and subthreshold attention-deficit/hyperactivity disorder (ADHD) among Korean children and adolescents.
A sample of 2,673 students was randomly selected from 19 representative schools in Seoul, Korea. The parents of the students completed the Diagnostic Interview Schedule for Children-version IV (DISC-IV), as well as questionnaires on perinatal and familial risk factors.
Maternal stress and alcohol use during pregnancy, parental marital discord, parental separation or divorce, changes in primary caregivers, and notbreastfeeding were significantly associated with full syndrome ADHD; however, maternal stress during pregnancy was the only variable that differentiated subthreshold ADHD from non-ADHD.
Our results provide evidence the perinatal and familial risk factors contribute to the development of ADHD in Korea children and adolescents, and suggest that these perinatal and familial risk factors are more closely related to full syndrome than to subthreshold ADHD.
本研究旨在探讨围产期和家族危险因素对韩国儿童和青少年全面综合征和亚临床注意缺陷多动障碍（ADHD）的影响。
从韩国首尔的 19 所代表性学校中随机抽取了 2673 名学生作为样本。学生的家长完成了儿童诊断访谈表第四版（DISC-IV），以及关于围产期和家族危险因素的问卷。
母亲在怀孕期间的压力和饮酒、父母婚姻不和、父母分居或离婚、主要照顾者的变化以及非母乳喂养与全面综合征 ADHD 显著相关；然而，只有母亲在怀孕期间的压力是区分亚临床 ADHD 与非 ADHD 的唯一变量。
我们的研究结果表明，围产期和家族危险因素可能导致韩国儿童和青少年出现 ADHD，并且这些围产期和家族危险因素与全面综合征的相关性高于与亚临床 ADHD 的相关性。
