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与 HCV 感染相关的横贯性脊髓炎。

Transverse myelitis associated to HCV infection.

机构信息

Clinica Médica, Hospital Universitário de Santa Maria, Rua dos Andradas no. 1125/301, Santa Maria, RS, Brazil.

出版信息

Braz J Infect Dis. 2009 Apr;13(2):147-52. doi: 10.1590/s1413-86702009000200015.

Abstract

Complications involving the central nervous system in patients suffering from hepatitis C virus (HCV) infection have been rare. Among them, it appears the transverse myelitis, which has already been reported in likely association with HCV. This paper presents the case study of a 65-year-old woman who developed cervical transverse myelitis linked to chronic HCV infection and anti-HCV antibodies in the spinal fluid, being excluded other etiologies for transverse myelitis. Current evidence has reinforced the likely association between chronic HCV infection and transverse myelitis, especially as recurrent manifestations of the disease. These findings reveal the need for more searching to establish the causal relationship between transverse myelitis and hepatitis C.

摘要

丙型肝炎病毒(HCV)感染患者的中枢神经系统并发症较为罕见。其中,已报道的横贯性脊髓炎可能与 HCV 有关。本文报告了一例 65 岁女性病例,该患者发生与慢性 HCV 感染和脑脊液中抗 HCV 抗体相关的颈段横贯性脊髓炎,排除了横贯性脊髓炎的其他病因。目前的证据加强了慢性 HCV 感染与横贯性脊髓炎之间的可能关联,尤其是作为该疾病的复发性表现。这些发现表明需要进一步研究以确定横贯性脊髓炎与丙型肝炎之间的因果关系。

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