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乙肝疫苗接种及呼吸道感染后早发性急性横贯性脊髓炎:病例报告

Early-onset acute transverse myelitis following hepatitis B vaccination and respiratory infection: case report.

作者信息

Fonseca Luiz Fernando, Noce Thelma Ribeiro, Teixeira Maria Letícia Gambogi, Teixeira Antônio Lúcio, Lana-Peixoto Marco Aurélio

机构信息

Centro Geral de Pediatria, FHEMIG, Belo Horizonte, MG, Brasil.

出版信息

Arq Neuropsiquiatr. 2003 Jun;61(2A):265-8. doi: 10.1590/s0004-282x2003000200020. Epub 2003 Jun 9.

DOI:10.1590/s0004-282x2003000200020
PMID:12806509
Abstract

Acute transverse myelitis is an acute inflammatory process of the spinal cord and it is a rare clinical syndrome in childhood. In this paper, we report a case of 3 years-old boy who developed acute onset tetraparesia following a viral respiratory infecction and hepatitis B vaccination. Magnetic resonance imaging of the spinal cord disclosed signal-intensity abnormalities from C4 to C3. A diagnosis of acute transverse myelitis was made and the patient was treated with IV methylprednisolone and IV immunoglobulin. The child had a fair outcome despite of the very acute course of the disease and the presence of a cervical sensory level which usually harbor a poor prognosis.

摘要

急性横贯性脊髓炎是脊髓的一种急性炎症性疾病,是儿童期罕见的临床综合征。本文报告一例3岁男孩,在发生病毒性呼吸道感染和接种乙肝疫苗后急性起病出现四肢瘫。脊髓磁共振成像显示C4至C3节段信号强度异常。诊断为急性横贯性脊髓炎,患者接受了静脉注射甲泼尼龙和静脉注射免疫球蛋白治疗。尽管病程非常急且存在颈髓感觉平面(通常预后较差),但该患儿预后良好。

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Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature.接种 SARS-CoV-2 疫苗后发生急性横贯性脊髓炎:病例报告及文献复习。
J Neurol. 2022 Mar;269(3):1121-1132. doi: 10.1007/s00415-021-10785-2. Epub 2021 Sep 5.
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Chronic fatigue syndrome and fibromyalgia following immunization with the hepatitis B vaccine: another angle of the 'autoimmune (auto-inflammatory) syndrome induced by adjuvants' (ASIA).
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Immunol Res. 2014 Dec;60(2-3):376-83. doi: 10.1007/s12026-014-8604-2.
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Acute disseminated encephalomyelitis: clinical and pathogenesis features.急性播散性脑脊髓炎:临床及发病机制特点
Neurol Clin. 2008 Aug;26(3):759-80, ix. doi: 10.1016/j.ncl.2008.03.009.