NYU Fertility Center, NYU School of Medicine, New York, NY 10016, USA.
J Assist Reprod Genet. 2010 Feb;27(2-3):69-74. doi: 10.1007/s10815-009-9382-y. Epub 2010 Feb 6.
As more reproductive-age women survive cancer at the expense of gonadotoxic therapy, the need for viable fertility preservation options has become paramount. Embryo cryopreservation, often using donor sperm, has been the standard offered these women over the past 20 years. Preservation of unfertilized oocytes now represents an acceptable and often equally viable alternative, particularly for single women, due to technologic advances made in the past decade. Given such, oocyte cryopreservation's experimental designation and need for IRB approval should thus be revisited.
随着越来越多的生育年龄女性在接受性腺毒性治疗的情况下幸存下来,对可行的生育力保存选择的需求变得至关重要。过去 20 年来,胚胎冷冻保存(通常使用供体精子)一直是为这些女性提供的标准选择。由于过去十年中取得的技术进步,未受精卵子的保存现在代表了一种可接受且同样可行的替代方案,特别是对于单身女性而言。鉴于此,应重新考虑卵母细胞冷冻保存的实验性指定和需要 IRB 批准的问题。