Faculty of Medicine, United Arab Emirates University, Al Ain, UAE.
Am J Drug Alcohol Abuse. 2010 Jan;36(1):7-12. doi: 10.3109/00952990903544786.
The aim of this work was to investigate the impact of life events on the profile of opioid dependent patients.
Recruitment was achieved through outpatient drug treatment clinic in Birmingham, UK, and data were collected through semistructured interviews. One-hundred and twenty subjects with opioid dependence syndrome were interviewed, and 100 controls of non-drug-using family members and friends.
The mean age of the opioid group was 33.3 years, SD = 8.8. The majority individuals of the sample were White British (80.8%), unemployed (69.2%), and male (75%). The mean severity of dependence as measured by two scales indicated severe level of dependence according to the authors of each scale. The mean number of traumatic events for the opioid dependence group was 4.8, SD = 3.57 vs. 3.55; SD = 3.65 in control group with significant difference (t = 2.56, df = 218, p = .01). Significant predictors of severe opioid dependency were age of second exposure to events, change of residence, break-up with boy/girlfriend, and conflict with father.
The data presented indicate that a significant group of opioid dependent patients experience adverse life events in both childhood and adulthood. It is by attending to and addressing these issues that health care workers can alleviate ongoing distress and promote confidence.
本研究旨在探讨生活事件对阿片类药物依赖患者特征的影响。
通过英国伯明翰的门诊药物治疗诊所进行招募，并通过半结构化访谈收集数据。对 120 名阿片类药物依赖综合征患者和 100 名非药物使用的家庭成员和朋友进行了访谈。
阿片类药物组的平均年龄为 33.3 岁，标准差=8.8。样本中的大多数个体是白种英国人（80.8%），失业（69.2%），男性（75%）。根据每个量表的作者，用两种量表测量的依赖严重程度的平均值表明存在严重程度的依赖。阿片类药物依赖组的平均创伤事件数为 4.8，标准差=3.57，对照组为 3.55，差异有统计学意义（t=2.56，df=218，p=0.01）。严重阿片类药物依赖的显著预测因素是第二次暴露于事件的年龄、居住地变更、与男/女朋友分手以及与父亲发生冲突。
目前的数据表明，相当一部分阿片类药物依赖患者在童年和成年期都经历过不良的生活事件。关注和解决这些问题可以减轻患者的持续痛苦，增强他们的信心。
