Walid M S
Medical Center of Central Georgia, 840 Pine Street, Suite 880, Macon, GA 31201, USA.
Indian J Nephrol. 2008 Oct;18(4):173-4. doi: 10.4103/0971-4065.45295.
Rhabdomyolysis, a potentially life-threatening syndrome, is not an uncommon condition with around 38,000 cases been reported in the USA in 2000. The risk of developing acute renal failure in the initial days of presentation can be as high as 40% and approximately 28-37% of patients require short-term hemodialysis. This report discusses a case of rhabdomyolysis after seizures in which blood urea nitrogen (BUN), creatinine, and BUN/creatinine levels were examined during the course of illness in the hospital. We found that the BUN/creatinine ratio is not a reliable indicator of renal function in rhabdomyolysis. Potassium levels can be a better marker for the early recognition of acute renal failure and an indication for prompt treatment with dialysis, which is crucial to prevent fatal complications.
横纹肌溶解症是一种潜在的危及生命的综合征,并非罕见病症,2000年美国报告了约38000例病例。在发病初期发生急性肾衰竭的风险可高达40%,约28% - 37%的患者需要短期血液透析。本报告讨论了一例癫痫发作后横纹肌溶解症的病例,该病例在住院期间对血尿素氮(BUN)、肌酐和BUN/肌酐水平进行了检查。我们发现,BUN/肌酐比值在横纹肌溶解症中并非肾功能的可靠指标。血钾水平可能是早期识别急性肾衰竭以及提示及时进行透析治疗的更好指标,这对于预防致命并发症至关重要。