Al-Shamsi Hanan N, Dueker David K, Nowilaty Sawsan R, Al-Shahwan Sami A
Department of Pediatric, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
Middle East Afr J Ophthalmol. 2009 Jan;16(1):15-9. doi: 10.4103/0974-9233.48860.
Neovascular glaucoma (NVG) is a severe form of secondary glaucoma caused by the growth of new vessels over the trabecular meshwork. The principal causes are associated with retinal ischemia. Ablative treatment of the retina can prevent, halt, and even reverse the growth of new vessels on the iris and angle. It is an essential part of the management in most cases.
To determine the causes of NVG among Saudi patients, presented at the King Khaled Eye Specialist Hospital.
A retrospective review of 337 Saudi patients with NVG was obtained. All cases were reviewed for the evidence and causes of the disease, and their basic demographic information. A subset of 100 diabetic patients with PDR was further studied in greater detail for clinical findings and treatment history.
The most common primary etiologic associations for NVG included diabetic retinopathy (DR) (56.06%), retinal venous obstruction (26.40%), and chronic retinal detachment (03.56%). A history of diabetes mellitus was reported in 65.04%, systemic arterial hypertension was noted in 61.00%, and evidence of renal impairment was documented in 22.00%. Vision was markedly reduced in most eyes with NVG (median: hand motion). The median best visual acuity in the fellow eye was 20/160. Among the 100 cases, with DR as a cause of NVG, 43 patients had bilateral neovascularization of the iris (NVI) and 72 had bilateral PDR. Sixty-one patients had no previous laser treatment before the diagnosis of NVG. Among these, who received treatment, the median number of total laser spots was 1,003.
Diabetes is a major cause of NVG presented to this tertiary eye care center in the Kingdom of Saudi Arabia followed by retinal venous obstruction. Close monitoring and full pan-retinal photocoagulation (PRP) were absent in most of the diabetic cases. It is important to recognize that the "unaffected" fellow eye, particularly in diabetic patients, may require fairly urgent treatment as well.
新生血管性青光眼（NVG）是一种由小梁网新生血管生长引起的严重继发性青光眼。主要病因与视网膜缺血有关。视网膜消融治疗可以预防、阻止甚至逆转虹膜和房角新生血管的生长。在大多数情况下，这是治疗的重要组成部分。
确定在沙特国王哈立德眼科专科医院就诊的沙特患者中NVG的病因。
对337例沙特NVG患者进行回顾性研究。所有病例均对疾病的证据和病因及其基本人口统计学信息进行了回顾。对100例糖尿病性增殖性视网膜病变（PDR）患者的子集进一步详细研究其临床发现和治疗史。
NVG最常见的主要病因包括糖尿病视网膜病变（DR）（56.06%）、视网膜静脉阻塞（26.40%）和慢性视网膜脱离（03.56%）。65.04%的患者有糖尿病病史，61.00%的患者有系统性动脉高血压，22.00%的患者有肾功能损害证据。大多数NVG患眼视力明显下降（中位数：手动）。对侧眼的最佳矫正视力中位数为20/160。在100例以DR为NVG病因的病例中，43例患者有双侧虹膜新生血管（NVI），72例有双侧PDR。61例患者在NVG诊断前未接受过激光治疗。在这些接受治疗的患者中，激光光斑总数的中位数为1003。
在沙特阿拉伯王国这个三级眼科护理中心，糖尿病是NVG的主要病因，其次是视网膜静脉阻塞。大多数糖尿病病例缺乏密切监测和全视网膜光凝（PRP）。重要的是要认识到，“未受影响”的对侧眼，尤其是糖尿病患者的对侧眼，可能也需要相当紧急的治疗。
