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新生血管性青光眼。病因学考量。

Neovascular glaucoma. Etiologic considerations.

作者信息

Brown G C, Magargal L E, Schachat A, Shah H

出版信息

Ophthalmology. 1984 Apr;91(4):315-20. doi: 10.1016/s0161-6420(84)34293-2.

DOI:10.1016/s0161-6420(84)34293-2
PMID:6201791
Abstract

A review of 208 patients with neovascular glaucoma (NVG) is presented. The most common primary etiologic associations included retinal venous obstructive disease (36.1%), diabetic retinopathy (32.2%), and carotid artery obstructive disease (12.9%). Systemic arterial hypertension was present in 51% and diabetes mellitus was noted in 46% of all patients. Among the 25 bilateral cases of NVG, 24 occurred in patients with diabetic retinopathy. Women comprised 65% of patients with NVG secondary to diabetes, and 57% of the venous obstruction group, while men accounted for 74% of cases in which NVG occurred secondary to carotid artery obstructive disease. Overall, 97% of eyes with NVG had a disease process that produced extensive retinal ischemia and preceded the onset of iris neovascularization. Patients with NVG, but without an obvious precipitating fundus condition, should be suspected of having severe carotid artery obstructive disease.

摘要

本文对208例新生血管性青光眼(NVG)患者进行了回顾性研究。最常见的原发性病因关联包括视网膜静脉阻塞性疾病(36.1%)、糖尿病视网膜病变(32.2%)和颈动脉阻塞性疾病(12.9%)。所有患者中,51%存在系统性动脉高血压,46%患有糖尿病。在25例双侧NVG病例中,24例发生于糖尿病视网膜病变患者。继发于糖尿病的NVG患者中女性占65%,静脉阻塞组中女性占57%,而继发于颈动脉阻塞性疾病的NVG病例中男性占74%。总体而言,97%的NVG患眼存在导致广泛视网膜缺血且先于虹膜新生血管形成的疾病过程。对于患有NVG但无明显眼底病变诱因的患者,应怀疑患有严重的颈动脉阻塞性疾病。

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