Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, CNRS UMR5246, Université Claude Bernard Lyon 1, 43 bd du 11 Novembre 1918, 69622 Villeurbanne, France.
Chemistry. 2010 Mar 1;16(9):2654-72. doi: 10.1002/chem.200902374.
Transition-metal-catalyzed C-H activation has recently emerged as a powerful tool for the functionalization of organic molecules. While many efforts have focused on the functionalization of arenes and heteroarenes by this strategy in the past two decades, much less research has been devoted to the activation of non-acidic C-H bonds of alkyl groups. This Minireview highlights recent work in this area, with a particular emphasis on synthetically useful methods.
过渡金属催化的 C-H 活化最近已成为有机分子功能化的有力工具。尽管在过去的二十年中，许多努力都集中在通过该策略对芳烃和杂芳烃进行官能化上，但对烷基中非酸性 C-H 键的活化研究却很少。这篇综述重点介绍了该领域的最新工作，特别强调了具有合成实用性的方法。
