• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

胰腺癌中的血管侵犯:影像学方法、术前诊断和手术处理。

Vascular invasion in pancreatic cancer: Imaging modalities, preoperative diagnosis and surgical management.

机构信息

Clinic for Visceral and Transplantation Surgery, Department of Surgery, University Hospitals of Geneva, 24, rue Micheli-du-Crest, 1211 Geneva 14, Switzerland.

出版信息

World J Gastroenterol. 2010 Feb 21;16(7):818-31. doi: 10.3748/wjg.v16.i7.818.

DOI:10.3748/wjg.v16.i7.818
PMID:20143460
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2825328/
Abstract

Pancreatic cancer is associated with a poor prognosis, and surgical resection remains the only chance for curative therapy. In the absence of metastatic disease, which would preclude resection, assessment of vascular invasion is an important parameter for determining resectability of pancreatic cancer. A frequent error is to misdiagnose an involved major vessel. Obviously, surgical exploration with pathological examination remains the "gold standard" in terms of evaluation of resectability, especially from the point of view of vascular involvement. However, current imaging modalities have improved and allow detection of vascular invasion with more accuracy. A venous resection in pancreatic cancer is a feasible technique and relatively reliable. Nevertheless, a survival benefit is not achieved by curative resection in patients with pancreatic cancer and vascular invasion. Although the discovery of an arterial invasion during the operation might require an aggressive management, discovery before the operation should be considered as a contraindication. Detection of vascular invasion remains one of the most important challenges in pancreatic surgery. The aim of this article is to provide a complete review of the different imaging modalities in the detection of vascular invasion in pancreatic cancer.

摘要

胰腺癌预后不良,手术切除仍然是唯一有治愈机会的治疗方法。在没有转移疾病(这会排除切除)的情况下,评估血管侵犯是确定胰腺癌可切除性的一个重要参数。一个常见的错误是错误诊断受累的主要血管。显然,手术探查并进行病理检查仍然是评估可切除性的“金标准”,特别是从血管受累的角度来看。然而,目前的成像方式已经得到了改善,可以更准确地检测血管侵犯。在胰腺癌中进行静脉切除是一种可行的技术,相对可靠。然而,在有血管侵犯的胰腺癌患者中,通过根治性切除并不能获得生存获益。尽管在手术过程中发现动脉侵犯可能需要积极的治疗,但在手术前发现应被视为禁忌。检测血管侵犯仍然是胰腺外科的最重要挑战之一。本文的目的是全面回顾不同的成像方式在胰腺癌血管侵犯检测中的应用。

相似文献

1
Vascular invasion in pancreatic cancer: Imaging modalities, preoperative diagnosis and surgical management.胰腺癌中的血管侵犯:影像学方法、术前诊断和手术处理。
World J Gastroenterol. 2010 Feb 21;16(7):818-31. doi: 10.3748/wjg.v16.i7.818.
2
Escalating computed tomography angiogram (CTA) grade predicts unresectability and margin status for pancreaticobiliary neoplasms.增强计算机断层扫描血管造影(CTA)分级可预测胰胆管肿瘤的不可切除性和切缘状态。
HPB (Oxford). 2010 Mar;12(2):115-22. doi: 10.1111/j.1477-2574.2009.00145.x.
3
Endosonography is superior to angiography in the preoperative assessment of vascular involvement among patients with pancreatic carcinoma.在胰腺癌患者血管受累情况的术前评估中,内镜超声检查优于血管造影。
J Clin Gastroenterol. 2001 Jan;32(1):54-8. doi: 10.1097/00004836-200101000-00013.
4
Pretherapeutic evaluation of patients with upper gastrointestinal tract cancer using endoscopic and laparoscopic ultrasonography.使用内镜超声和腹腔镜超声对上消化道癌患者进行治疗前评估。
Dan Med J. 2012 Dec;59(12):B4568.
5
[MRI in the evaluation of peripancreatic vessel invasion and resectability of pancreatic carcinoma].[磁共振成像在评估胰腺癌胰周血管侵犯及可切除性中的应用]
Zhonghua Zhong Liu Za Zhi. 2007 Nov;29(11):846-9.
6
[Prospective evaluation of the clinical significance of ultrasonography, helical computed tomography, magnetic resonance imaging and endoscopic ultrasonography in the assessment of vascular invasion and lymph node metastasis of pancreatic carcinoma].[超声、螺旋计算机断层扫描、磁共振成像及内镜超声在评估胰腺癌血管侵犯及淋巴结转移中的临床意义的前瞻性研究]
Zhonghua Zhong Liu Za Zhi. 2008 Sep;30(9):682-5.
7
Computed tomography-based vascular burden index as a predictor of vascular resection and pathological vascular invasion in pancreatic cancer with neo-adjuvant chemotherapy.基于计算机断层扫描的血管负担指数预测新辅助化疗后胰腺癌的血管切除和病理血管侵犯。
Eur J Surg Oncol. 2024 Sep;50(9):108494. doi: 10.1016/j.ejso.2024.108494. Epub 2024 Jun 20.
8
[Endosonography in the T-staging of pancreatic cancer].
Khirurgiia (Mosk). 2014(8):16-22.
9
Surgery for Pancreatic Cancer.胰腺癌手术
Hematol Oncol Clin North Am. 2015 Aug;29(4):701-16. doi: 10.1016/j.hoc.2015.04.001. Epub 2015 May 30.
10
EUS diagnosis of vascular invasion in pancreatic cancer: surgical and histologic correlates.超声内镜诊断胰腺癌血管侵犯:手术及组织学相关性
Am J Gastroenterol. 2005 Jun;100(6):1381-5. doi: 10.1111/j.1572-0241.2005.41675.x.

引用本文的文献

1
Clinical outcomes of preservation versus resection of portal/superior mesenteric vein during pancreaticoduodenectomy in pancreatic cancer patients who respond to neoadjuvant treatment: a retrospective cohort study.新辅助治疗有反应的胰腺癌患者在胰十二指肠切除术中门静脉/肠系膜上静脉保留与切除的临床结局:一项回顾性队列研究
Int J Surg. 2024 Nov 1;110(11):7150-7158. doi: 10.1097/JS9.0000000000002034.
2
Surgical Indications and Outcomes of Resection for Pancreatic Neuroendocrine Tumors with Vascular Involvement.伴有血管侵犯的胰腺神经内分泌肿瘤切除术的手术指征及结果
Cancers (Basel). 2022 May 6;14(9):2312. doi: 10.3390/cancers14092312.
3
Pancreatic adenocarcinoma: A review of recent paradigms and advances in epidemiology, clinical diagnosis and management.胰腺导管腺癌:流行病学、临床诊断和治疗的最新模式和进展综述。
World J Gastroenterol. 2021 Jun 21;27(23):3158-3181. doi: 10.3748/wjg.v27.i23.3158.
4
Distal Pancreatectomy with Celiac Axis Resection: Systematic Review and Meta-Analysis.联合腹腔干切除术的远端胰腺切除术:系统评价与荟萃分析
Cancers (Basel). 2021 Apr 19;13(8):1967. doi: 10.3390/cancers13081967.
5
The Bromodomain Inhibitor, INCB057643, Targets Both Cancer Cells and the Tumor Microenvironment in Two Preclinical Models of Pancreatic Cancer.溴结构域抑制剂INCB057643在两种胰腺癌临床前模型中对癌细胞和肿瘤微环境均有作用。
Cancers (Basel). 2020 Dec 30;13(1):96. doi: 10.3390/cancers13010096.
6
Use of imaging as staging and surgical planning for pancreatic surgery.将影像学用于胰腺手术的分期及手术规划。
Hepatobiliary Surg Nutr. 2020 Oct;9(5):603-614. doi: 10.21037/hbsn.2019.05.04.
7
A promising tool for T-staging of lung cancer: Is convex probe endobronchial ultrasound superior to computed tomography in detecting invasion of mediastinal and hilar vessels?一种用于肺癌T分期的有前景的工具:凸阵探头支气管内超声在检测纵隔和肺门血管侵犯方面是否优于计算机断层扫描?
Turk Gogus Kalp Damar Cerrahisi Derg. 2019 Jun 17;27(3):355-359. doi: 10.5606/tgkdc.dergisi.2019.16987. eCollection 2019 Jul.
8
Endoscopic Ultrasonography for Vascular Invasion in Pancreatic Cancer.用于检测胰腺癌血管侵犯的内镜超声检查
Clin Endosc. 2019 Sep;52(5):397-398. doi: 10.5946/ce.2019.142. Epub 2019 Aug 13.
9
High-resolution intravascular MRI-guided perivascular ultrasound ablation.高分辨率血管内 MRI 引导的血管周围超声消融术。
Magn Reson Med. 2020 Jan;83(1):240-253. doi: 10.1002/mrm.27932. Epub 2019 Aug 11.
10
Preoperative CT findings for prediction of resectability in patients with gallbladder cancer.术前 CT 表现预测胆囊癌患者的可切除性。
Eur Radiol. 2019 Dec;29(12):6458-6468. doi: 10.1007/s00330-019-06323-4. Epub 2019 Jun 28.

本文引用的文献

1
Diagnostic value of EUS-FNA in patients suspected of having pancreatic cancer with a focal lesion on CT scan/MRI but without obstructive jaundice.超声内镜引导下细针穿刺活检(EUS-FNA)对CT扫描/MRI显示有局灶性病变但无梗阻性黄疸的疑似胰腺癌患者的诊断价值
Pancreas. 2009 Aug;38(6):625-30. doi: 10.1097/MPA.0b013e3181ac35d2.
2
Neoadjuvant 5 fluorouracil-cisplatin chemoradiation effect on survival in patients with resectable pancreatic head adenocarcinoma: a ten-year single institution experience.新辅助5-氟尿嘧啶-顺铂同步放化疗对可切除性胰头腺癌患者生存的影响:一项单机构十年经验
Oncology. 2009;76(6):413-9. doi: 10.1159/000215928. Epub 2009 May 4.
3
Vascular invasion in pancreatic cancer: evaluation of endoscopic ultrasonography, computed tomography, ultrasonography, and angiography.胰腺癌中的血管侵犯:内镜超声、计算机断层扫描、超声及血管造影的评估
Swiss Med Wkly. 2007 May 19;137(19-20):286-91. doi: 10.4414/smw.2007.11701.
4
Distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic body cancer: long-term results.联合腹腔干整块切除的远端胰腺切除术治疗局部进展期胰体癌:长期结果
Ann Surg. 2007 Jul;246(1):46-51. doi: 10.1097/01.sla.0000258608.52615.5a.
5
Significance of the depth of portal vein wall invasion after curative resection for pancreatic adenocarcinoma.胰腺癌根治性切除术后门静脉壁侵犯深度的意义
Arch Surg. 2007 Feb;142(2):172-9; discussion 180. doi: 10.1001/archsurg.142.2.172.
6
Clinical implications of combined portal vein resection as a palliative procedure in patients undergoing pancreaticoduodenectomy for pancreatic head carcinoma.联合门静脉切除作为胰头癌患者胰十二指肠切除术姑息性手术的临床意义。
Ann Surg Oncol. 2006 Dec;13(12):1569-78. doi: 10.1245/s10434-006-9143-4.
7
Postoperative morbidity and long-term survival after pancreaticoduodenectomy with superior mesenterico-portal vein resection.肠系膜上静脉-门静脉切除的胰十二指肠切除术后的术后发病率和长期生存率。
J Gastrointest Surg. 2006 Sep-Oct;10(8):1106-15. doi: 10.1016/j.gassur.2006.04.002.
8
Extended pancreatectomy with resection of the celiac axis: the modified Appleby operation.扩大胰切除术联合腹腔干切除:改良Appleby手术
Am J Surg. 2006 Sep;192(3):330-5. doi: 10.1016/j.amjsurg.2006.05.010.
9
Pancreaticoduodenectomy with mesentericoportal vein resection for adenocarcinoma of the pancreatic head.胰十二指肠切除术联合肠系膜门静脉切除治疗胰头腺癌
World J Surg. 2006 Aug;30(8):1526-35. doi: 10.1007/s00268-005-0784-4.
10
Pancreatic adenocarcinoma: signs of vascular invasion determined by multi-detector row CT.胰腺腺癌:多层螺旋CT确定的血管侵犯征象
Br J Radiol. 2006 Nov;79(947):880-7. doi: 10.1259/bjr/19684199. Epub 2006 Jul 5.