Suppr超能文献

[16个Y染色体短串联重复序列(Y-STRs)标记在波兰中部人群中的应用]

[The utility of the 16 Y-STRS markers in the central Poland population].

作者信息

Jacewicz Renata, Jedrzejczyk Maciej, Babol-Pokora Katarzyna, Piatek Jarosław, Ossowski Andrzej, Berent Jarosław

机构信息

Pracownia Genetyki Sadowej Katedry i Zakładu Medycyny Sadowej Uniwersytetu Medycznego w Lodzi, ul. Sedziowska 18 a, 91-304 Łódź.

出版信息

Ann Acad Med Stetin. 2007;53 Suppl 2:95-101.

Abstract

Haplotype and allele frequencies for the panel of 16 Y-chromosome STR loci, namely DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and Y GATA-H4 were determined in a population sample of 250 unrelated males from the central region of Poland. The 238 different haplotypes were identified, of which 227 haplotypes were unique, 10 were duplicated and one haplotype was shared between three unrelated men. The average gene diversity was 0.5995, combined gene diversity was 0.9998 and probability that two randomly chosen haplotypes are different in the population was 0.9996. Interpopulation comparisons revealed that Polish population is homogeneous within the three compared samples, while it differs statistically significantly from other population samples apart from Spanish population. This seems to be the first report showing the analysis of the molecular genetic distance between the population of Poland and other European and world populations for the panel of 16 Y-chromosome STR loci. The analyzed set of Y-STR markers is very useful in forensic casework to identify males and trace paternal lineages.

摘要

在来自波兰中部地区的250名无关男性的群体样本中,测定了16个Y染色体STR基因座(即DYS19、DYS385、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393、DYS437、DYS438、DYS439、DYS448、DYS456、DYS458、DYS635和Y GATA - H4)的单倍型和等位基因频率。共鉴定出238种不同的单倍型,其中227种单倍型是独特的,10种是重复的,还有一种单倍型在三个无关男性之间共享。平均基因多样性为0.5995,组合基因多样性为0.9998,在该群体中随机选择的两个单倍型不同的概率为0.9996。群体间比较显示,波兰群体在三个比较样本中是同质的,而与除西班牙群体外的其他群体样本在统计学上有显著差异。这似乎是第一篇展示对波兰群体与其他欧洲和世界群体之间16个Y染色体STR基因座分子遗传距离进行分析的报告。所分析的Y - STR标记集在法医案件工作中对于识别男性和追踪父系谱系非常有用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验