年龄相关的龛细胞变化影响造血干细胞功能。
Age-related changes in niche cells influence hematopoietic stem cell function.
机构信息
Department of Internal Medicine and Markey Cancer Center, University of Kentucky, 800 Rose Street, Lexington, KY 40536, USA.
出版信息
Cell Stem Cell. 2010 Feb 5;6(2):93-4. doi: 10.1016/j.stem.2010.01.008.
PMID:20144780
Abstract
In a recent issue of Nature, Mayack et al. (2010) use young and old parabiotic mice to show that systemic signals from the young parabiont rejuvenate hematopoietic stem cell function via the microenvironmental niche.
摘要
在最近一期的《自然》杂志上，Mayack 等人（2010 年）使用年轻和年老的联体共生小鼠表明，来自年轻共生体的系统信号通过微环境龛使造血干细胞功能年轻化。
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