特布他林对雾化喷他脒诱导的支气管收缩的作用。
Effect of terbutaline on bronchoconstriction induced by nebulised pentamidine.
作者信息
Leigh T R, Wiggins J, Gazzard B G, Collins J V
机构信息
Westminster Hospital, London.
出版信息
Thorax. 1991 Feb;46(2):122-3. doi: 10.1136/thx.46.2.122.
The severity, duration, and reversibility of pentamidine induced bronchial narrowing was studied with and without pretreatment with nebulised terbutaline 10 mg in an open study of 40 patients seropositive for the human immunodeficiency virus (HIV). All subjects received pentamidine 300 mg in 5 ml water via an Acorn System 22 jet nebuliser. The forced expiratory volume in one second (FEV1) fell in all 20 patients given pentamidine alone, the mean maximum fall being 20.6%. In the 20 patients given pentamidine preceded by nebulised terbutaline the mean maximum fall in FEV1 was 4%; three subjects had a fall in FEV1 of more than 10%.
在一项针对40名人类免疫缺陷病毒（HIV）血清学阳性患者的开放性研究中，研究了喷他脒诱导的支气管狭窄的严重程度、持续时间和可逆性，部分患者在使用喷他脒前雾化吸入10mg特布他林，部分患者未进行该预处理。所有受试者均通过Acorn System 22喷射雾化器将300mg喷他脒溶于5ml水中吸入。仅接受喷他脒治疗的20名患者的一秒用力呼气量（FEV1）均下降，平均最大降幅为20.6%。在雾化吸入特布他林后再接受喷他脒治疗的20名患者中，FEV1的平均最大降幅为4%；三名受试者的FEV1降幅超过10%。
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