Population Health Research Unit, Research Centre of the Laval University Affiliated Hospital, Québec, Canada.
Rheumatology (Oxford). 2010 May;49(5):945-54. doi: 10.1093/rheumatology/kep469. Epub 2010 Feb 8.
To examine the change in pain and function related to the knee scheduled for surgery, change in health-related quality of life (HRQoL) and change in contralateral knee pain during pre-surgery wait up until time of surgery.
One hundred and fifty-three patients scheduled for knee replacement were recruited from three hospitals in Québec City, Canada, and followed until surgery. Pre-surgery wait, defined as the time between enrolment on the pre-surgery wait list and surgery, was considered in five categories (< or =3, >3-6, >6-9, >9-12 and >12 months). Pain and functional limitations were measured with the Western Ontario and McMaster Osteoarthritis Index (WOMAC) and HRQoL was measured with the medical outcomes study 36-item short form health survey.
Mean pre-surgery wait time was 183 (s.d. 121.9) days. Subjects having waited >9-12 months showed significant deterioration of the WOMAC pain (-9.9; 95% CI -19.2, -0.54) and function (-11.1; 95% CI -18.7, -3.4) scores. On the HRQoL SF-36 physical functioning scale, a significant deterioration was seen in subjects having waited >9-12 months (-11.3; 95% CI -18.4, -4.2) and >12 months (-7.1; 95% CI -12.9, -1.3). On the contralateral knee WOMAC pain score, a significant deterioration was observed in subjects having waited >6-9 months (-10.4; 95% CI -16.9, -3.9) and >12 months (-10.7; 95% CI -19.7, -1.7).
Pre-surgery wait time has a negative significant impact on pain, function and HRQoL at the time of surgery. The magnitude of deterioration seen in this study may be clinically important. The effects of this pre-surgery deterioration on post-surgery outcomes need to be investigated.
研究膝关节手术前等待期间疼痛和功能的变化、健康相关生活质量(HRQoL)的变化以及对侧膝关节疼痛的变化。
从加拿大魁北克市的 3 家医院招募了 153 名计划接受膝关节置换的患者,并对其进行随访直至手术。手术前等待期(从登记手术前等待名单到手术的时间)被分为 5 个类别(<=3、>3-6、>6-9、>9-12 和>12 个月)。疼痛和功能障碍采用 Western Ontario 和 McMaster 骨关节炎指数(WOMAC)进行测量,健康相关生活质量采用医疗结局研究 36 项简短健康调查问卷进行测量。
平均手术前等待时间为 183(标准差 121.9)天。等待>9-12 个月的患者 WOMAC 疼痛(-9.9;95%CI -19.2,-0.54)和功能(-11.1;95%CI -18.7,-3.4)评分显著恶化。在 HRQoL SF-36 生理功能量表上,等待>9-12 个月(-11.3;95%CI -18.4,-4.2)和>12 个月(-7.1;95%CI -12.9,-1.3)的患者生理功能评分显著恶化。在对侧膝关节 WOMAC 疼痛评分方面,等待>6-9 个月(-10.4;95%CI -16.9,-3.9)和>12 个月(-10.7;95%CI -19.7,-1.7)的患者疼痛评分显著恶化。
手术前等待时间对手术时的疼痛、功能和 HRQoL 有显著的负面影响。本研究中观察到的恶化程度可能具有临床意义。需要研究这种手术前恶化对手术后结果的影响。