The primary cilium at a glance.
作者信息
Satir Peter, Pedersen Lotte B, Christensen Søren T
机构信息
Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, 10461 NY, USA.
出版信息
J Cell Sci. 2010 Feb 15;123(Pt 4):499-503. doi: 10.1242/jcs.050377.
Abstract
摘要
相似文献
1
The primary cilium at a glance.初级纤毛概览。
J Cell Sci. 2010 Feb 15;123(Pt 4):499-503. doi: 10.1242/jcs.050377.
2
Making sense of cilia and flagella.解读纤毛和鞭毛。
J Cell Biol. 2007 Nov 19;179(4):575-82. doi: 10.1083/jcb.200709039.
3
Role of primary cilia in the pathogenesis of polycystic kidney disease.原发性纤毛在多囊肾病发病机制中的作用。
J Am Soc Nephrol. 2007 May;18(5):1381-8. doi: 10.1681/ASN.2006111215. Epub 2007 Apr 11.
4
The perennial organelle: assembly and disassembly of the primary cilium.永恒的细胞器：初级纤毛的组装与拆卸。
J Cell Sci. 2010 Feb 15;123(Pt 4):511-8. doi: 10.1242/jcs.061093.
5
A physiological view of the primary cilium.初级纤毛的生理学观点。
Annu Rev Physiol. 2005;67:515-29. doi: 10.1146/annurev.physiol.67.040403.101353.
6
Novel functions of the primary cilium in bone disease and cancer.原发性纤毛在骨病和癌症中的新功能。
Cytoskeleton (Hoboken). 2019 Mar;76(3):233-242. doi: 10.1002/cm.21529. Epub 2019 May 28.
7
Ciliary ectosomes: transmissions from the cell's antenna.睫状外泌体：来自细胞“天线”的传递物质
Trends Cell Biol. 2015 May;25(5):276-85. doi: 10.1016/j.tcb.2014.12.008. Epub 2015 Jan 21.
8
The emerging complexity of the vertebrate cilium: new functional roles for an ancient organelle.脊椎动物纤毛日益复杂的情况：一种古老细胞器的新功能作用
Dev Cell. 2006 Jul;11(1):9-19. doi: 10.1016/j.devcel.2006.06.009.
9
Cilia: tuning in to the cell's antenna.纤毛：倾听细胞的天线
Curr Biol. 2006 Aug 8;16(15):R604-14. doi: 10.1016/j.cub.2006.07.012.
10
Emerging roles for renal primary cilia in epithelial repair.肾脏初级纤毛在上皮修复中的新兴作用。
Int Rev Cell Mol Biol. 2012;293:169-93. doi: 10.1016/B978-0-12-394304-0.00011-7.
引用本文的文献
1
Platelet-derived growth factor signaling in porcine testicular tubular somatic cells.猪睾丸曲细精管体细胞中的血小板源性生长因子信号传导
Cell Tissue Res. 2025 Aug 21. doi: 10.1007/s00441-025-04004-x.
2
Primary cilia and their role in preeclampsia.原发性纤毛及其在子痫前期中的作用。
Int J Med Sci. 2025 Jul 10;22(13):3260-3267. doi: 10.7150/ijms.114433. eCollection 2025.
3
The MEC-2E isoform with a large C-terminal completely rescues the touch sensation defect of C. elegans.具有大的C末端的MEC-2E同种型完全挽救了秀丽隐杆线虫的触觉感觉缺陷。
Sci Rep. 2025 Jul 22;15(1):26606. doi: 10.1038/s41598-025-10711-w.
4
Ciliary G-Protein Coupled Receptor Signaling in Polycystic Kidney Disease.多囊肾病中的纤毛G蛋白偶联受体信号传导
Int J Mol Sci. 2025 May 22;26(11):4971. doi: 10.3390/ijms26114971.
5
Bioinformatics analyses of the proteome of coelomic fluid and the first evidence of primary cilium in coelomocyte cells.体腔液蛋白质组的生物信息学分析及体腔细胞中初级纤毛的首个证据。
Front Immunol. 2025 May 15;16:1539751. doi: 10.3389/fimmu.2025.1539751. eCollection 2025.
6
White Adipocyte Stem Cell Expansion Through Infant Formula Feeding: New Insights into Epigenetic Programming Explaining the Early Protein Hypothesis of Obesity.通过婴儿配方奶粉喂养实现白色脂肪干细胞扩增：肥胖早期蛋白质假说的表观遗传编程新见解
Int J Mol Sci. 2025 May 8;26(10):4493. doi: 10.3390/ijms26104493.
7
Fabrication of 3D matrix microenvironment by two-photon lithography for mechanobiology study.用于力学生物学研究的双光子光刻三维基质微环境的制备
Mechanobiol Med. 2023 Jul 7;1(1):100010. doi: 10.1016/j.mbm.2023.100010. eCollection 2023 Sep.
8
Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols.通过对不同方案的人诱导多能干细胞衍生模型进行基于成像的系统分析揭示的神经元纤毛发生率和纤毛含量差异。
Front Cell Dev Biol. 2025 Apr 11;13:1516596. doi: 10.3389/fcell.2025.1516596. eCollection 2025.
9
Disrupted glucocorticoid receptor cell signalling causes a ciliogenesis defect in the fetal mouse renal tubule.糖皮质激素受体细胞信号传导中断会导致胎鼠肾小管的纤毛发生缺陷。
EMBO Rep. 2025 Apr 17. doi: 10.1038/s44319-025-00454-0.
10
Ciliary Ion Channels in Polycystic Kidney Disease.多囊肾病中的睫状体离子通道
Cells. 2025 Mar 19;14(6):459. doi: 10.3390/cells14060459.
本文引用的文献
1
Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts.在对血小板衍生生长因子-AA（PDGF-AA）的伤口愈合反应中，成纤维细胞中的初级纤毛协调细胞的定向迁移和趋化作用。
Cell Physiol Biochem. 2010;25(2-3):279-92. doi: 10.1159/000276562. Epub 2010 Jan 12.
2
Adult type 3 adenylyl cyclase-deficient mice are obese.成年 3 型腺苷酸环化酶缺乏症小鼠肥胖。
PLoS One. 2009 Sep 11;4(9):e6979. doi: 10.1371/journal.pone.0006979.
3
Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.初级纤毛既能介导又能抑制刺猬信号通路依赖性肿瘤发生。
Nat Med. 2009 Sep;15(9):1055-61. doi: 10.1038/nm.2011. Epub 2009 Aug 23.
4
Dual and opposing roles of primary cilia in medulloblastoma development.原发性纤毛在髓母细胞瘤发生发展中的双重对立作用
Nat Med. 2009 Sep;15(9):1062-5. doi: 10.1038/nm.2020. Epub 2009 Aug 23.
5
Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes.生长停滞在3T3-L1前脂肪细胞分化诱导过程中诱导初级纤毛形成并使IGF-1受体信号敏感化。
J Cell Sci. 2009 Aug 1;122(Pt 15):2760-8. doi: 10.1242/jcs.046276. Epub 2009 Jul 13.
6
SnapShot: Intraflagellar transport.简要概述：鞭毛内运输
Cell. 2009 May 15;137(4):784-784.e1. doi: 10.1016/j.cell.2009.04.053.
7
Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells.释放的核苷酸放大了 MDCK 细胞中依赖纤毛和流动诱导的 [Ca2+]i 反应。
Acta Physiol (Oxf). 2009 Nov;197(3):241-51. doi: 10.1111/j.1748-1716.2009.02002.x. Epub 2009 May 11.
8
The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium.原发性纤毛中通过血小板衍生生长因子受体α（PDGFR-α）刺激的定向迁移需要Na+/H+交换体NHE1。
J Cell Biol. 2009 Apr 6;185(1):163-76. doi: 10.1083/jcb.200806019.
9
The vertebrate primary cilium in development, homeostasis, and disease.脊椎动物初级纤毛在发育、稳态及疾病中的作用
Cell. 2009 Apr 3;137(1):32-45. doi: 10.1016/j.cell.2009.03.023.
10
Primary cilia and signaling pathways in mammalian development, health and disease.哺乳动物发育、健康与疾病中的初级纤毛及信号通路。
Nephron Physiol. 2009;111(3):p39-53. doi: 10.1159/000208212. Epub 2009 Mar 10.
Zotero 插件