法国某医院产超广谱 AmpCβ-内酰胺酶的 ST23 复合群 A 型大肠埃希菌的发生。
Occurrence of ST23 complex phylogroup A Escherichia coli isolates producing extended-spectrum AmpC beta-lactamase in a French hospital.
机构信息
Service de Bactériologie-Hygiène, CHU de Nantes, Nantes, France.
出版信息
Antimicrob Agents Chemother. 2010 May;54(5):2216-8. doi: 10.1128/AAC.01580-09. Epub 2010 Feb 9.
Abstract
Extended-spectrum AmpC beta-lactamase (ESAC) Escherichia coli producers were investigated over a 5-year period. Eleven isolates presenting a strong ampC promoter and different strategic AmpC mutations, including two newly described modifications (A292V and an L-A-A insertion at 295), were characterized. All the isolates belonged to phylogenetic group A and to the ST23 complex.
摘要
在过去的 5 年中，对产超广谱 AmpCβ-内酰胺酶（ESAC）的大肠杆菌进行了研究。研究了 11 株具有强 AmpC 启动子和不同策略 AmpC 突变的分离株，包括两种新描述的修饰（A292V 和 295 位的 L-A-A 插入）。所有分离株均属于 A 群和 ST23 复合体。
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