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In Vivo Evolution of CMY-2 to CMY-33 β-Lactamase in Escherichia coli Sequence Type 131: Characterization of an Acquired Extended-Spectrum AmpC Conferring Resistance to Cefepime.大肠杆菌序列型131中CMY-2向CMY-33β-内酰胺酶的体内进化：一种获得性超广谱AmpC对头孢吡肟耐药性的特征分析

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本文引用的文献

1

MLST typing of Escherichia coli isolates overproducing AmpC {beta}-lactamase.高产AmpC β-内酰胺酶的大肠杆菌分离株的多位点序列分型

J Antimicrob Chemother. 2009 Jun;63(6):1290-2. doi: 10.1093/jac/dkp099. Epub 2009 Mar 22.

2

Emergence of extended-spectrum-AmpC-expressing Escherichia coli isolates in Belgian hospitals.比利时医院中表达超广谱AmpC的大肠杆菌分离株的出现。

J Antimicrob Chemother. 2009 May;63(5):1073-5. doi: 10.1093/jac/dkp046. Epub 2009 Feb 24.

3

Extended-spectrum cephalosporinases: structure, detection and epidemiology.超广谱头孢菌素酶：结构、检测与流行病学

Future Microbiol. 2007 Jun;2(3):297-307. doi: 10.2217/17460913.2.3.297.

4

Most Escherichia coli strains overproducing chromosomal AmpC beta-lactamase belong to phylogenetic group A.大多数过量产生染色体AmpCβ-内酰胺酶的大肠杆菌菌株属于系统发育A组。

J Antimicrob Chemother. 2007 Oct;60(4):872-6. doi: 10.1093/jac/dkm284. Epub 2007 Jul 27.

5

Extension of the hydrolysis spectrum of AmpC beta-lactamase of Escherichia coli due to amino acid insertion in the H-10 helix.由于H-10螺旋中氨基酸插入导致大肠杆菌AmpCβ-内酰胺酶水解谱的扩展。

J Antimicrob Chemother. 2007 Sep;60(3):490-4. doi: 10.1093/jac/dkm227. Epub 2007 Jun 22.

6

Naturally occurring extended-spectrum cephalosporinases in Escherichia coli.大肠杆菌中天然存在的超广谱头孢菌素酶

Antimicrob Agents Chemother. 2006 Jul;50(7):2573-6. doi: 10.1128/AAC.01633-05.

7

Detection of plasmid-mediated AmpC beta-lactamase genes in clinical isolates by using multiplex PCR.运用多重聚合酶链反应检测临床分离株中质粒介导的AmpCβ-内酰胺酶基因

J Clin Microbiol. 2002 Jun;40(6):2153-62. doi: 10.1128/JCM.40.6.2153-2162.2002.

8

Analysis of the effects of -42 and -32 ampC promoter mutations in clinical isolates of Escherichia coli hyperproducing ampC.大肠埃希菌高产AmpC临床分离株中-42和-32 AmpC启动子突变的影响分析

J Antimicrob Chemother. 2000 Jun;45(6):783-8. doi: 10.1093/jac/45.6.783.

法国某医院产超广谱 AmpCβ-内酰胺酶的 ST23 复合群 A 型大肠埃希菌的发生。

Occurrence of ST23 complex phylogroup A Escherichia coli isolates producing extended-spectrum AmpC beta-lactamase in a French hospital.

机构信息

Service de Bactériologie-Hygiène, CHU de Nantes, Nantes, France.

出版信息

Antimicrob Agents Chemother. 2010 May;54(5):2216-8. doi: 10.1128/AAC.01580-09. Epub 2010 Feb 9.

DOI:10.1128/AAC.01580-09

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2863611/

Abstract

Extended-spectrum AmpC beta-lactamase (ESAC) Escherichia coli producers were investigated over a 5-year period. Eleven isolates presenting a strong ampC promoter and different strategic AmpC mutations, including two newly described modifications (A292V and an L-A-A insertion at 295), were characterized. All the isolates belonged to phylogenetic group A and to the ST23 complex.

摘要

在过去的 5 年中，对产超广谱 AmpCβ-内酰胺酶（ESAC）的大肠杆菌进行了研究。研究了 11 株具有强 AmpC 启动子和不同策略 AmpC 突变的分离株，包括两种新描述的修饰（A292V 和 295 位的 L-A-A 插入）。所有分离株均属于 A 群和 ST23 复合体。