Delvaux Michel, Gay Gérard
Department of Internal Medicine and Digestive Pathology, Hôpitaux de Brabois Adultes, Tour Drouet, CHU de Nancy, F-54511 Vandoeuvre-les-Nancy, France.
Best Pract Res Clin Gastroenterol. 2008;22(5):813-37. doi: 10.1016/j.bpg.2008.06.003.
Since it was introduced in 2000, capsule endoscopy has become the gold standard for endoscopic examination of the small bowel in several clinical situations such as obscure gastrointestinal bleeding, suspicion of Crohn's disease, and surveillance of polyposis syndromes. In this technique a miniaturised endoscope, embedded in a swallowable capsule, is propelled through the gut by peristalsis and reaches the right colon in 5-8h. Images captured by the capsule are recorded on a hard drive in a belt worn by the patient. In addition to the extensive literature currently available on small bowel CE, new capsule devices are currently under evaluation for the examination of the colon with the purpose of screening for colorectal cancer, and of the oesophagus for screening for oesophageal varices and Barrett's oesophagus. These latter indications currently remain under evaluation. This review considers the technical aspects of capsule endoscopy and discusses the indications. Issues of safety and tolerance are also discussed.
自2000年问世以来，胶囊内镜已成为多种临床情况下小肠内镜检查的金标准，如不明原因的胃肠道出血、疑似克罗恩病以及息肉病综合征的监测。在这项技术中，一个嵌入可吞咽胶囊内的微型内镜通过蠕动在肠道内推进，并在5至8小时内到达右半结肠。胶囊拍摄的图像记录在患者佩戴的腰带上的硬盘中。除了目前关于小肠胶囊内镜的大量文献外，目前正在评估新型胶囊设备用于结肠检查，目的是筛查结直肠癌，以及用于食管检查以筛查食管静脉曲张和巴雷特食管。这些后期的适应证目前仍在评估中。本综述考虑了胶囊内镜的技术方面并讨论了适应证。还讨论了安全性和耐受性问题。
