Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
Org Lett. 2010 Mar 5;12(5):1140-3. doi: 10.1021/ol1001818.
A hydrogen bonding-mediated double Michael addition-aromatization cascade of 2-propenylindoles and nitroolefins has been disclosed. The methodology allows an efficient synthesis of diverse and structurally complex tetrahydrocarbazoles in good to excellent enantioselectivities and diastereoselectivities.
一种氢键介导的 2-丙烯基吲哚和硝基烯烃的双迈克尔加成-芳构化级联反应已经被揭示。该方法能够高效合成具有不同结构的复杂四氢咔唑化合物，具有良好到优秀的对映选择性和非对映选择性。
