Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcaste upon Tyne NE2 4HH, UK.
Rheumatology (Oxford). 2010 May;49(5):844-53. doi: 10.1093/rheumatology/keq009. Epub 2010 Feb 10.
Chronic fatigue is one of the most prevalent and debilitating symptoms in primary SS (pSS). Approximately 70% of pSS patients suffer from disabling fatigue, which is associated with reduced health-related quality of life. In this article, we review the instruments used for evaluating pSS-related fatigue, our current understanding of the underlying psychosocial and physiological mechanisms of fatigue in pSS and the therapeutic strategies that have been studied in the management of fatigue in pSS.
慢性疲劳是原发性干燥综合征（pSS）中最常见和最具致残性的症状之一。约 70%的 pSS 患者患有致残性疲劳，这与健康相关的生活质量降低有关。本文综述了用于评估 pSS 相关疲劳的工具，以及我们目前对 pSS 中疲劳的潜在心理社会和生理机制的理解，以及在 pSS 疲劳管理中研究过的治疗策略。
