Malhotra Raman, Then Siew-Yin, Richards Alison, Cheek Elizabeth
Corneoplastic Unit, Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead, West Sussex RH19 3DZ, UK.
Open Ophthalmol J. 2010 Jan 15;4:1-6. doi: 10.2174/1874364101004010001.
To test the hypothesis that occlusion-positive (OP) patients with blepharospasm (BEB) or hemifacial spasm (HFS) will benefit from a Bangerter occlusion foil (BOF), compared to occlusion-negative (ON) patients. OP/ON was based on immediate improvement in spasm with placement of a hand in front of either eye.
Prospective non-randomised single-centre pilot study.
Fifteen-patients (6 BEB, 9 HFS).
Patients were identified as OP or ON and wore highest-density BOF tolerable over one spectacle lens for 1 month. Outcomes were assessed at 1 month.
Validated quality-of-life questionnaire (CDQ-24), scores of blink-rate and spasm severity assessed by two observers from video-recordings.
OP group had mean improvement in all scores. There was no change or worsening of scores in the ON group. In both BEB and HFS, more OP patients reported subjective benefit from wearing a foil (2 of 4 BEB, and 2 of 2 HFS) compared to the ON group (0 of 2 BEB, and 1 of 7 HFS).
OP patients with BEB and HFS are more likely to experience improvement in spasms from wearing a BOF compared to ON patients. The occlusion test should be considered on all patients with BEB or HFS.
检验以下假设，即与闭眼阴性（ON）患者相比，眼睑痉挛（BEB）或面肌痉挛（HFS）的闭眼阳性（OP）患者将从班格特遮挡箔片（BOF）中获益。OP/ON基于将手置于任一眼前方时痉挛立即改善来判定。
前瞻性非随机单中心试验研究。
15名患者（6例BEB，9例HFS）。
将患者判定为OP或ON，并在一副眼镜镜片上佩戴可耐受的最高密度BOF，持续1个月。在1个月时评估结果。
经过验证的生活质量问卷（CDQ - 24）、由两名观察者根据视频记录评估的眨眼率和痉挛严重程度得分。
OP组所有得分均有平均改善。ON组得分无变化或恶化。在BEB和HFS中，与ON组（2例BEB中0例，7例HFS中1例）相比，更多OP患者报告佩戴箔片有主观获益（4例BEB中2例，2例HFS中2例）。
与ON患者相比，BEB和HFS的OP患者更有可能因佩戴BOF而使痉挛得到改善。应对所有BEB或HFS患者进行遮挡试验。
