Autism Centre for Young Children, Handicap and Habilitation and Karolinska University Hospital, Stockholm, Sweden.
Res Dev Disabil. 2010 May-Jun;31(3):680-5. doi: 10.1016/j.ridd.2010.01.007. Epub 2010 Feb 10.
The aims of this study were to estimate prevalence rates of children with autism spectrum disorder (ASD) diagnoses in a cohort of 6-year-old children with birth year 2002, referred to the Autism Centre for Young Children, serving the whole of Stockholm county and on the basis of the available data discuss clinical aspects of assessment, habilitation and follow-up. Records of 142 of a total of 147 (123 boys and 24 girls) identified children with ASD diagnoses were scrutinised with respect to type of diagnosis, cognitive level, other developmental disorders and medical/neurological disorders. The overall prevalence of such disorders was 6.2/1000 (95% confidence interval 5.2-7.2/1000). The rates of learning disability/mental retardation, developmental delay without a specified cognitive level and normal intelligence constituted about one third, respectively. AS and atypical autism tended to be diagnosed more often at age 5-6 years while AD with learning disability/mental retardation was more often diagnosed at age 3-4 years. The awareness of ASDs has resulted in increasing numbers of children being diagnosed at young ages. We conclude that it is important to take into account these children's broader developmental profiles, need for repeated assessment of cognitive functions and follow-up over time and also the requirement for medical/neurological consideration and work-up.
本研究的目的是估计在一个出生于 2002 年的 6 岁儿童队列中,患有自闭症谱系障碍 (ASD) 的儿童的患病率。这些儿童被转诊到服务于整个斯德哥尔摩县的儿童自闭症中心,并根据现有数据讨论评估、康复和随访的临床方面。对 147 名确诊为 ASD 的儿童中的 142 名(123 名男孩和 24 名女孩)的记录进行了审查,内容涉及诊断类型、认知水平、其他发育障碍和医疗/神经障碍。这些障碍的总体患病率为 6.2/1000(95%置信区间为 5.2-7.2/1000)。学习障碍/智力迟钝、未指定认知水平的发育迟缓以及正常智力的比例分别约为三分之一。AS 和非典型自闭症倾向于在 5-6 岁时被诊断,而伴有学习障碍/智力迟钝的 AD 则更倾向于在 3-4 岁时被诊断。对 ASDs 的认识导致越来越多的儿童在年幼时被诊断出患有这种疾病。我们得出结论,重要的是要考虑这些儿童更广泛的发育概况、对认知功能进行重复评估以及随时间进行随访的需求,还需要考虑医疗/神经方面的问题并进行相应的检查。