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肺癌化疗患者的生活质量、症状体验和痛苦。

Quality of life, symptom experience and distress of lung cancer patients undergoing chemotherapy.

机构信息

Istanbul Bilim University, Florence Nightingale Hospital School of Nursing, Vefabey sokak No: 17, 34349 Gayrettepe/Besiktas, Istanbul, Turkey.

出版信息

Eur J Oncol Nurs. 2010 Dec;14(5):400-9. doi: 10.1016/j.ejon.2010.01.003. Epub 2010 Feb 10.

DOI:10.1016/j.ejon.2010.01.003
PMID:20149733
Abstract

UNLABELLED

The diagnosis of lung cancer in the advanced stage of illness, the poor prognosis associated with the disease, and the side effects of chemotherapy all have an impact on various dimensions of quality of life (QoL).

THE PURPOSE OF THE RESEARCH

The current study was designed to describe the QoL and symptom distress of lung cancer patients undergoing chemotherapy and to explore the relationships between demographic/treatment-related characteristics and QoL.

METHODS AND SAMPLE

The sample consisted of 154 lung cancer patients undergoing chemotherapy. The symptom experiences and QoL of lung cancer patients undergoing chemotherapy were evaluated using the Memorial Symptom Assessment Scale and Quality of Life Index - Cancer Version.

RESULTS

The lung cancer patients had low QoL scores. The scores on the Health and Functioning subscale were the lowest (20.33 ± 5.59), while those of the Family subscale were the highest (27.66 ± 2.77). The most common physical symptoms experienced by lung cancer patients were lack of energy, coughing, pain, lack of appetite, and nausea, while the psychological symptoms were feeling nervous, difficulty sleeping, feeling sad, and worrying. There was a negative relationship between the symptom distress and quality of life scores (r=-0.45; p<0.000). Females and those with low income levels and performance status experienced greater symptom distress.

CONCLUSIONS

Lung cancer patients receiving chemotherapy suffer many limitations due to the symptoms and disruptions to their QoL, arising from both the disease process and its treatment. Lung cancer patients need to be assessed regularly and supported.

摘要

目的:本研究旨在描述接受化疗的肺癌患者的生活质量(QoL)和症状困扰,并探讨人口统计学/治疗相关特征与 QoL 之间的关系。

方法和样本:该样本由 154 名正在接受化疗的肺癌患者组成。采用 Memorial 症状评估量表和癌症生活质量指数评估肺癌患者的症状体验和 QoL。

结果:肺癌患者的 QoL 评分较低。健康和功能子量表的评分最低(20.33±5.59),而家庭子量表的评分最高(27.66±2.77)。肺癌患者最常见的身体症状是乏力、咳嗽、疼痛、食欲不振和恶心,而心理症状是紧张、睡眠困难、悲伤和担忧。症状困扰与生活质量评分呈负相关(r=-0.45;p<0.000)。女性、收入水平低和身体状况差的患者经历更大的症状困扰。

结论:接受化疗的肺癌患者由于疾病过程及其治疗导致的症状和生活质量下降,受到许多限制。需要定期评估和支持肺癌患者。

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