5-羟色胺 1A 自身受体功能改变与抗抑郁反应。
Altered function of the serotonin 1A autoreceptor and the antidepressant response.
机构信息
University of Ottawa Institute of Mental Health Research, Ottawa, ON K1Z 7K4, Canada.
出版信息
Neuron. 2010 Jan 14;65(1):1-2. doi: 10.1016/j.neuron.2009.12.028.
PMID:20152106
Abstract
In this issue of Neuron, Richardson-Jones et al. report on a novel genetic approach to conditionally and specifically dampen the function of the 5-HT(1A) autoreceptor in mice to study its role on the 5-HT system and on the antidepressant-like effect of the selective serotonin reuptake inhibitor (SSRI) fluoxetine.
摘要
在本期《神经元》杂志中，Richardson-Jones 等人报告了一种新的遗传方法，用于条件性和特异性地抑制小鼠 5-HT(1A)自身受体的功能，以研究其在 5-HT 系统中的作用以及选择性 5-羟色胺再摄取抑制剂 (SSRI) 氟西汀的抗抑郁样作用。
Zotero 插件