癌症幸存者的代谢综合征。

The metabolic syndrome in cancer survivors.

机构信息

Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.

出版信息

Lancet Oncol. 2010 Feb;11(2):193-203. doi: 10.1016/S1470-2045(09)70287-6.

DOI:10.1016/S1470-2045(09)70287-6

PMID:20152771

Abstract

The metabolic syndrome, as a cluster of cardiovascular risk factors, may represent an important connection between cancer treatment and its common late effect of cardiovascular disease. Insight into the aetiology of the metabolic syndrome after cancer treatment might help to identify and treat cancer survivors with increased cardiovascular risk. In this review, we summarise current knowledge on the prevalence and pathophysiology of the metabolic syndrome in cancer survivors, and discuss current intervention strategies with an emphasis on new developments.

摘要

代谢综合征作为一组心血管危险因素，可能代表了癌症治疗与其常见的心血管疾病晚期并发症之间的重要联系。深入了解癌症治疗后代谢综合征的病因学可能有助于识别和治疗心血管风险增加的癌症幸存者。在这篇综述中，我们总结了目前关于癌症幸存者中代谢综合征的患病率和病理生理学的知识，并讨论了当前的干预策略，重点介绍了新的发展。