Department of Medicine, University of Alberta, Canada.
Vaccine. 2010 Apr 1;28(16):2841-5. doi: 10.1016/j.vaccine.2010.01.056. Epub 2010 Feb 12.
We reviewed how health economics has been included in the vaccine expert review processes in a sample of countries. We identified two kinds of review processes - those in which vaccines and drugs are assessed using a common process, and those in which vaccines are assessed within the infectious disease framework. In either process, the countries recommend that their national pharmaco-economic (i.e., guidelines developed for drugs) guidelines be used to conduct the studies, although the guidelines themselves differ between countries. As a result of these factors, the decision process and the study outcomes can differ between countries, but because the vaccine adoption process includes other criteria as well, economic factors will not necessarily alter the outcome.
我们回顾了在一系列国家中，卫生经济学是如何被纳入疫苗专家审查流程的。我们发现了两种审查流程——一种是使用共同流程评估疫苗和药物，另一种是在传染病框架内评估疫苗。在任何一种流程中，这些国家都建议使用其国家药物经济学（即针对药物制定的指南）指南来进行研究，尽管这些指南在各国之间存在差异。由于这些因素，决策过程和研究结果可能在各国之间存在差异，但由于疫苗采用过程还包括其他标准，因此经济因素不一定会改变结果。
