Department of Pediatrics, University of Alberta, Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada.
Curr Opin Neurol. 2010 Apr;23(2):97-102. doi: 10.1097/WCO.0b013e3283372430.
Early detection and diagnosis of autism spectrum disorders (ASDs) allows opportunities for children and their families to benefit more fully from early supports and interventions.
Recent advances in early detection research have resulted from prospective studies of high-risk infants and large ASD screening studies conducted in community settings. With improvement in early detection of autism, exciting progress has been made in establishing the efficacy of ASD-specific interventions for toddlers as young as 18 months on the basis of controlled clinical trials.
There has been increasing emphasis on opportunities to link early behavioral expression to the underlying neurobiology of ASD, potentially bringing us closer to the fundamental mechanisms underlying this disorder.
自闭症谱系障碍(ASD)的早期检测和诊断为儿童及其家庭提供了充分受益于早期支持和干预的机会。
早期检测研究的最新进展来自于对高危婴儿的前瞻性研究和在社区环境中进行的大型 ASD 筛查研究。随着自闭症早期检测的改进,在基于对照临床试验的情况下,对于 18 个月大的幼儿,ASD 特异性干预措施的疗效已经取得了令人兴奋的进展。
越来越强调将早期行为表现与 ASD 的潜在神经生物学联系起来,这可能使我们更接近这种疾病的基本机制。