National Institute of Health Sciences, Tokyo 158-8501, Japan.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Mar;27(3):365-72. doi: 10.1080/19440040903317497.
The intake of total aflatoxins (AFT) and aflatoxin B(1) (AFB(1)) from food in Japan was estimated from AFT and AFB(1) concentration and frequency data in 24 foods (884 samples) from a 3-year retail market survey from the summer of 2004 to the winter of 2006, and by food consumption data from the National Health and Nutrition Survey performed in 2005. The AFT and AFB(1) survey revealed that peanut, peanut products, cocoa, chocolate, pistachio, white pepper, red pepper, almond, job's tears, buckwheat and corn grits are considered to be contributors of AFT (or AFB(1)) intake in Japan (maximum AFB(1) (AFT) levels ranged from 0.21 to 28.0 microg kg(-1) (from 0.21 to 9.0 microg kg(-1))) in AFT-contaminated food. A probabilistic approach using the Monte Carlo method was carried out to simulate an estimate of the AFT (or AFB(1)) intake distributions in each age group in Japan. In this study, AFB(1) intake ranged from 0.003 to 0.004 ng kg(-1) body weight day(-1) (from lower to upper limits), and the potential risk for cancer using a formula devised by the Joint Food and Agricultural Organization/World Health Organization (FAO/WHO) Expert Committee on Food Additives (JECFA) was estimated at 0.00004-0.00005 person/year/100,000 persons, even though this was in the higher levels (95.0th percentile) of the consumer population. The results suggest that the current dietary intake of AFB(1) in Japan has no appreciable effect on health.
从 2004 年夏季到 2006 年冬季的 3 年零售市场调查中，从 24 种食品（884 个样本）中检测了总黄曲霉毒素（AFT）和黄曲霉毒素 B1（AFB1）的浓度和频率数据，并结合 2005 年全国健康和营养调查的食品消费数据，估算了日本人从食物中摄入的总黄曲霉毒素（AFT）和黄曲霉毒素 B1（AFB1）的情况。AFT 和 AFB1 调查显示，花生、花生制品、可可、巧克力、开心果、白胡椒、红胡椒、杏仁、薏米、荞麦和玉米糁被认为是日本 AFT（或 AFB1）摄入的来源（最高 AFB1（AFT）水平范围为 0.21 至 28.0μg/kg（0.21 至 9.0μg/kg））在受污染的食物中。使用蒙特卡罗方法进行了概率方法，以模拟日本人在各个年龄组中的 AFT（或 AFB1）摄入分布的估计值。在这项研究中，AFB1 摄入量从 0.003 到 0.004ng/kg 体重/天（下限到上限）不等，使用粮农组织/世界卫生组织（FAO/WHO）食品添加剂联合专家委员会（JECFA）制定的公式估计癌症的潜在风险为 0.00004-0.00005 人/年/10 万人，尽管这是在消费者人群的较高水平（95.0 百分位数）。结果表明，目前日本人从饮食中摄入的 AFB1 对健康没有明显影响。
