成束蛋白和MADM：一种新型生长调节复合体？
Bunched and Madm: a novel growth-regulatory complex?
作者信息
Harvey Kieran F
机构信息
Cell Growth and Proliferation Laboratory, Peter MacCallum Cancer Centre, 7 St Andrews Place, East Melbourne, Victoria 3002, Australia.
出版信息
J Biol. 2010;9(1):8. doi: 10.1186/jbiol219. Epub 2010 Feb 11.
Abstract
By combining Drosophila genetics and proteomics Gluderer et al. report in this issue of Journal of Biology the isolation of a novel growth-regulatory complex consisting of Bunched and Madm. Future study of this complex will address the precise mechanism of growth control, regulation of complex activity, the interface with other growth pathways and a potential role in human cancer.
摘要
通过结合果蝇遗传学和蛋白质组学，格鲁德雷尔等人在本期《生物学杂志》上报告了一种由Bunched和Madm组成的新型生长调节复合物的分离。对该复合物的进一步研究将揭示生长控制的确切机制、复合物活性的调节、与其他生长途径的关联以及在人类癌症中的潜在作用。
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