Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.
Brain. 2010 Mar;133(Pt 3):909-14. doi: 10.1093/brain/awq011. Epub 2010 Feb 15.
Conjugate eye deviation describes the tonic horizontal deviation of the eyes in acute stroke patients. Here we investigate whether measuring patients' eye-in-head position in clinical magnetic resonance imaging or computed tomography scans obtained at admission shows a specific relationship to spatial neglect. We investigated 124 continuously admitted subjects with unilateral, first-ever left- or right-sided stroke. To control for the possibility that the degree of eye deviation is related to lesion size rather than spatial neglect, overall lesion volume was used as a covariate in the statistical analysis. Horizontal eye-in-head deviation on clinical brain scans appeared to be associated with spatial neglect rather than with brain damage per se. In contrast to the subject groups without the disorder, the patients with spatial neglect showed an eye-in-head position that was significantly deviated towards the ipsilesional right. Evaluation of eye-in-head position on clinical scans thus may be an additional helpful tool for diagnosing spatial neglect, particularly in the very early period of the stroke.
共轭眼偏斜描述了急性中风患者眼睛的紧张性水平偏斜。在这里，我们研究了在入院时获得的临床磁共振成像或计算机断层扫描中测量患者头部眼睛位置是否与空间忽略有特定关系。我们调查了 124 名连续入院的单侧、首次左侧或右侧中风患者。为了控制眼偏斜程度与病变大小相关而不是与空间忽略相关的可能性，在统计分析中，整体病变体积被用作协变量。临床脑部扫描上的水平眼位偏斜似乎与空间忽略有关，而与大脑损伤本身无关。与没有该疾病的患者组相比，空间忽略患者的头部眼睛位置明显偏向同侧右侧。因此，在临床扫描上评估头部眼睛位置可能是诊断空间忽略的另一个有用工具，特别是在中风的早期阶段。
