Makos Monique A, Kuklinski Nicholas J, Berglund E Carina, Heien Michael L, Ewing Andrew G
Department of Chemistry, The Pennsylvania State University, 125 Chemistry Building, University Park, PA 16802, USA.
Trends Analyt Chem. 2009 Dec 1;28(11):1223-1234. doi: 10.1016/j.trac.2009.08.005.
The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry and technologies involving intact organisms, including in vivo electrochemistry.
果蝇，即黑腹果蝇，已被广泛用作遗传学研究中的模式生物，并在理解人类行为的分子、细胞和进化方面做出了重大贡献。最近，研究集中在开发分析方法，以从黑腹果蝇中获得高灵敏度的化学定量以及时空信息。我们综述了毛细管电泳、高效液相色谱、质谱以及包括体内电化学在内的涉及完整生物体的技术方面的一些进展。
