通过与瓦克反应相关的氧化反应两步合成具有苯并二氮杂卓/γ-氨基丁酸能活性的黄酮类化合物。
A two step synthesis of BzR/GABAergic active flavones via a Wacker-related oxidation.
作者信息
Lorenz Michael, Kabir M Shahjahan, Cook James M
机构信息
Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, USA.
出版信息
Tetrahedron Lett. 2010 Feb 17;51(7):1095. doi: 10.1016/j.tetlet.2009.12.107.
Abstract
A general route for the synthesis of biologically important flavones is reported via a two step sequence employing a catalytic Wacker-Cook oxidation4b as the key step.
摘要
据报道，通过以催化瓦克-库克氧化反应4b为关键步骤的两步反应序列，可得到合成具有重要生物学意义的黄酮类化合物的通用路线。
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