Dabur Rajesh, Gupta Amita, Mandal T K, Singh Desh Deepak, Bajpai Vivek, Gurav A M, Lavekar G S
Regional Research Institute (Ay), Nehru Garden, Kothrud, Pune-411 038.
Afr J Tradit Complement Altern Med. 2007 Feb 16;4(3):313-8. doi: 10.4314/ajtcam.v4i3.31225.
The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of Acacia nilotica, Justicia zelanica, Lantana camara and Saraca asoca exhibited good activity against all the bacteria tested and the MIC was recorded in range of 9.375-37.5 microg/ml and 75.0-300.0 microg/ml against the bacterial and fungal pathogens, respectively. The other extracts of Phyllanthus urinaria, Thevetia nerifolia, Jatropha gossypifolia Saraca asoca, Tamarindus indica, Aegle marmelos, Acacia nilotica, Chlorophytum borivilianum, Mangifera indica, Woodfordia fruticosa and Phyllanthus emblica showed antimicrobial activity in a range of 75-1200 microg/ml.
采用微量肉汤稀释法,对来自24种植物的77种提取物针对8种细菌和4种致病真菌的抗菌潜力进行了筛选。在用对碘硝基四氮唑紫处理后抑制任何可见微生物生长的提取物最低浓度,被视为最低抑菌浓度(MIC)。阿拉伯金合欢、泽兰爵床、马缨丹和无忧花的水提取物对所有测试细菌均表现出良好活性,对细菌病原体的MIC记录在9.375 - 37.5微克/毫升范围内,对真菌病原体的MIC记录在75.0 - 300.0微克/毫升范围内。叶下珠、黄花夹竹桃、棉叶麻风树、无忧花、罗望子、木苹果、阿拉伯金合欢、波维吊兰、芒果、铁筷子和余甘子的其他提取物显示出75 - 1200微克/毫升范围内的抗菌活性。