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大戟乳胶中环阿尔廷-24-烯-3β-醇对淡水鱼斑鳢神经酶乙酰胆碱酯酶和氧化代谢的影响

Effect of cycloart-24-en-3beta-ol from Euphorbia royleana latex on neuroenzyme AChE and oxidative metabolism of freshwater fish, Channa punctatus.

作者信息

Tiwari Sudhanshu, Pandey Rp, Singh Ajay

机构信息

Department of Zoology, D.D.U. Gorakhpur University Gorakhpur-273009, UP, India.

出版信息

Afr J Tradit Complement Altern Med. 2008 Jun 18;5(4):332-9. doi: 10.4314/ajtcam.v5i4.31287.

DOI:10.4314/ajtcam.v5i4.31287
PMID:20161954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2816582/
Abstract

Cycloart-24-en-3beta-ol isolated from Euphorbia royleana latex possesses potent piscicidal activity against freshwater predatory fish Channa punctatus. Their short as well as long-term exposure causes significant (P<0.05) time and dose-dependent reversible alteration in the oxidative metabolism of the fish Channa punctatus Cycloart-24-en-3beta-ol also shifts fish respiratory pathway, inhibits energy production and AChE activity reversibly may be advantageous for their use as environmentally safe piscicide for controlling the predatory fish C. punctatus population from carp culture ponds.

摘要

从大戟乳胶中分离出的环阿屯-24-烯-3β-醇对淡水掠食性鱼类斑鳢具有强大的毒鱼活性。它们的短期和长期暴露会导致斑鳢的氧化代谢发生显著（P<0.05）的时间和剂量依赖性可逆变化。环阿屯-24-烯-3β-醇还会改变鱼类的呼吸途径，可逆地抑制能量产生和乙酰胆碱酯酶活性，这可能有利于将其用作环境安全的杀鱼剂，以控制鲤鱼养殖池塘中掠食性鱼类斑鳢的数量。

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