Int J Mol Sci. 2010 Jan 12;11(1):154-63. doi: 10.3390/ijms11010154.
Imagine devices or particles so small that they are invisible to the naked eye. Imagine that such entities could be used to patrol our bodies and autonomously augment endogenous defense and repair mechanisms. Imagine the defeat of illness at a fraction of the current costs. Bionanotechnology is the field of science that deals with just that: the development of imaging, tracking, targeting, sensing, diagnostic, and eventually therapeutic capabilities based on particles in the nanometer range, i.e., "nanoparticles". Within the extensive group of nanoparticles, semiconducting quantum dots play a central and prominent role. Quantum dots excel at a myriad of physical properties, most notably their fluorescent properties, such as high quantum yield, photo-stability, broad absorption spectra, and their remarkable size-dependent emission-tunability.
想象一下,有这样的设备或粒子,小到肉眼无法看到。想象一下,这些微小的实体可以被用来在我们体内巡逻,并自主增强内源性防御和修复机制。想象一下,以目前成本的一小部分就能战胜疾病。生物纳米技术就是研究这个的科学领域:基于纳米范围内的粒子(即“纳米粒子”)来开发成像、跟踪、靶向、传感、诊断和最终治疗的能力。在广泛的纳米粒子群体中,半导体量子点起着核心和突出的作用。量子点在许多物理性质方面表现出色,尤其是它们的荧光性质,例如高量子产率、光稳定性、宽吸收光谱以及显著的尺寸相关发射可调谐性。