Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Am J Addict. 2010 Mar-Apr;19(2):111-8. doi: 10.1111/j.1521-0391.2009.00015.x.
The National Drug Abuse Treatment Clinical Trials Network (CTN) recently completed a randomized, open label trial comparing treatment as usual (TAU) combined with nicotine patches plus cognitive behavioral group counseling for smoking cessation (n = 153) to TAU alone (n = 72) for patients enrolled in treatment programs for drug or alcohol dependence, who were interested in quitting smoking. This report is a secondary analysis evaluating the effect of depressive symptomatology (n = 70) or history of depression (n = 110) on smoking cessation outcomes. A significant association was seen between measures of depression and difficulty quitting cigarettes. Specifically, there was a greater probability for smoking abstinence for those with lower baseline Beck Depression Inventory II (BDI-II) scores. These data suggest that evaluation and treatment of depressive symptoms may play an important role in improving smoking cessation outcomes. (Am J Addict 2010;00:1-8).
国家药物滥用治疗临床试验网络（CTN）最近完成了一项随机、开放标签试验，比较了常规治疗（TAU）联合尼古丁贴片加认知行为团体咨询戒烟（n = 153）与单独 TAU（n = 72）对参加药物或酒精依赖治疗计划并有意戒烟的患者的效果。本报告是对评估抑郁症状（n = 70）或抑郁史（n = 110）对戒烟结果的影响的二次分析。抑郁症状的测量与戒烟困难之间存在显著关联。具体来说，基线贝克抑郁量表二（BDI-II）评分较低的患者，戒烟的可能性更大。这些数据表明，评估和治疗抑郁症状可能在改善戒烟效果方面发挥重要作用。（美国成瘾杂志 2010；00:1-8）。
