Department of Veterinary Public Health and Food Safety, Food and Veterinary Toxicology Unit and WHO/FAO Collaborating Centre for Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy.
Zoonoses Public Health. 2010 Dec;57(7-8):e136-42. doi: 10.1111/j.1863-2378.2009.01309.x.
The modern concept of zoonosis considers any detriment to the health and/or quality of human life resulting from relationships with (other) vertebrate or edible or toxic invertebrate animals. Whereas exposure to toxicants through foods of animal origin (a.o.) is a well-established issue, hereby we discuss it as novel zoonoses, from the standpoints of health implications as well as similarities and differences with classical zoonoses caused by biological agents. Novel toxicant-related zoonoses are linked with new issues in food safety, such as the environment-feed-food chain. In fact, the potential effect of the combined and repeated exposure to dietary toxicants is generally long-term and not readily discernible. Endocrine disrupting chemicals in staple foods of a.o. are discussed as a telling example of a food safety issue summing up critical points covered by the definition of sustainable development, also implicating health risks for generations to come. We suggest some critical points to implement the veterinary public health action in sustainable food safety, such as enhancement of Hazard Analysis and Critical Control Points systems for toxicological risk management.
现代人畜共患病的概念认为，任何由于与（其他）脊椎动物或可食用或有毒无脊椎动物的关系而对人类健康和/或生活质量造成的损害。虽然通过动物源性食品（如）接触毒物是一个既定的问题，但在此我们从健康影响以及与生物制剂引起的经典人畜共患病的相似性和差异的角度将其作为新的人畜共患病进行讨论。与食品安全新出现的问题有关的新型与毒物有关的人畜共患病与新出现的问题有关，例如环境-饲料-食物链。事实上，人们普遍认为，长期接触和重复接触饮食毒物的潜在影响是长期的，不易察觉的。我们讨论了如主食中的内分泌干扰化学物质等问题，这些问题是食品安全问题的一个典型例子，概括了可持续发展定义所涵盖的要点，也涉及到未来几代人的健康风险。我们提出了一些实施可持续食品安全兽医公共卫生行动的关键点，例如加强危害分析和关键控制点系统，以进行毒理学风险管理。
