Department of Ophthalmology, Osaka University Medical School, Suita, 565-0871, Japan.
J Glaucoma. 2010 Oct-Nov;19(8):551-5. doi: 10.1097/IJG.0b013e3181ca76f3.
To assess the usefulness of anterior segment optical coherence tomography (AS-OCT) in evaluating postoperative filtering bleb function.
Forty-eight eyes of 39 patients who had earlier undergone trabeculectomy were enrolled. Blebs were imaged with a commercially available AS-OCT system. The correlation between intraocular pressure (IOP) and 4 quantitative parameters, bleb height, bleb wall thickness, and the height and extent of internal cavity, and 2 qualitative parameters, bleb wall reflectivity, and the presence or absence of posterior episcleral fluid, were analyzed.
Of the 39 participants, 25 (64.1%) were males (mean age, 65.3±10.0 y). The height and extent of the internal cavity and the bleb height were not correlated with the IOP. The bleb wall thickness was negatively (P=0.004) correlated with the IOP. The mean IOP in eyes with a low-reflectivity bleb wall was significantly (P=0.001) lower than in eyes with a high-reflectivity wall. The IOP levels were significantly (P=0.008) lower in eyes with posterior episcleral fluid than in eyes without it.
AS-OCT is a useful tool to evaluate filtering bleb function. The height and extent of the total bleb and the internal cavity were not correlated with IOP control. A low-reflectivity wall and the presence of episcleral fluid were associated with lower IOP.
评估眼前节光学相干断层扫描（AS-OCT）在评估术后滤过泡功能中的作用。
纳入 39 例（48 只眼）曾行小梁切除术的患者。使用商业 AS-OCT 系统对滤过泡进行成像。分析眼内压（IOP）与 4 个定量参数（滤过泡高度、滤过泡壁厚度以及内部腔的高度和范围）和 2 个定性参数（滤过泡壁反射率和是否存在后巩膜积液）之间的相关性。
39 名参与者中，男性 25 例（64.1%）（平均年龄 65.3±10.0 岁）。内部腔的高度和范围以及滤过泡高度与 IOP 均无相关性。滤过泡壁厚度与 IOP 呈负相关（P=0.004）。低反射滤过泡壁的平均眼压显著（P=0.001）低于高反射滤过泡壁。存在后巩膜积液眼的 IOP 水平显著（P=0.008）低于无积液眼。
AS-OCT 是评估滤过泡功能的有用工具。总滤过泡和内部腔的高度和范围与 IOP 控制无关。低反射壁和巩膜积液的存在与较低的 IOP 相关。
