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用于阴道前壁脱垂的猪皮胶原蛋白植入物：一项随机前瞻性对照研究。

Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study.

作者信息

Hviid Ulla, Hviid Thomas Vauvert F, Rudnicki Martin

机构信息

Department of Obstetrics and Gynaecology, Roskilde University Hospital, Roskilde, Denmark.

出版信息

Int Urogynecol J. 2010 May;21(5):529-34. doi: 10.1007/s00192-009-1018-3. Epub 2010 Feb 18.

DOI:10.1007/s00192-009-1018-3
PMID:20165833
Abstract

INTRODUCTION AND HYPOTHESIS

The effect of a Pelvicol graft compared with a conventional anterior vaginal repair was evaluated in this randomised controlled study.

METHODS

Only patients with a stage II or higher (Ba >or= -1) defect were included.

RESULTS

Thirty-one patients were allocated to a conventional anterior repair; 30 to Pelvicol graft. At 12 months follow-up, four patients among controls (15%) and two in the graft group (7%) had objective recurrence. Among controls, the difference at 3 months follow-up in Ba was 6.0 cm when compared with the position of Ba prior to surgery. In the graft group, the difference was 7.0 cm (P < 0.05). This difference was still present at 12 months follow-up (6.0 vs. 7.0 cm; P < 0.05).

CONCLUSIONS

The implantation of a Pelvicol graft does not improve the POP-Q stage.

摘要

引言与假设

在这项随机对照研究中，评估了Pelvicol移植物与传统阴道前壁修补术相比的效果。

方法

仅纳入II期或更高分期（Ba≥ -1）缺损的患者。

结果

31例患者被分配至传统阴道前壁修补组；30例被分配至Pelvicol移植物组。在12个月的随访中，对照组中有4例患者（15%）出现客观复发，移植物组中有2例（7%）。在对照组中，与术前Ba的位置相比，3个月随访时Ba的差异为6.0厘米。在移植物组中，差异为7.0厘米（P<0.05）。在12个月的随访中，这种差异仍然存在（6.0对7.0厘米；P<0.05）。

结论

植入Pelvicol移植物并不能改善盆腔器官脱垂定量分期（POP-Q分期）。

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2
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Int Urogynecol J Pelvic Floor Dysfunct. 2008 Jun;19(6):787-93. doi: 10.1007/s00192-007-0526-2.
3
Results of cystocele repair: a comparison of traditional anterior colporrhaphy, polypropylene mesh and porcine dermis.
女性盆底功能障碍的管理：医疗器械综述与评估
Interface Focus. 2019 Aug 6;9(4):20190014. doi: 10.1098/rsfs.2019.0014. Epub 2019 Jun 14.
4
A systematic review of outcome and outcome-measure reporting in randomised trials evaluating surgical interventions for anterior-compartment vaginal prolapse: a call to action to develop a core outcome set.一项关于评估前盆腔脏器脱垂手术干预的随机试验中结局及结局指标报告的系统评价：呼吁制定核心结局集。
Int Urogynecol J. 2018 Dec;29(12):1727-1745. doi: 10.1007/s00192-018-3781-5. Epub 2018 Oct 22.
5
Surgery for women with pelvic organ prolapse with or without stress urinary incontinence.针对患有或未患有压力性尿失禁的盆腔器官脱垂女性的手术。
Cochrane Database Syst Rev. 2018 Aug 19;8(8):CD013108. doi: 10.1002/14651858.CD013108.
6
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Int Urogynecol J. 2018 Jun;29(6):781-788. doi: 10.1007/s00192-017-3510-5. Epub 2017 Dec 6.
7
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9
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4
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Int Urogynecol J Pelvic Floor Dysfunct. 2007 Mar;18(3):245-9. doi: 10.1007/s00192-006-0133-7. Epub 2006 Jul 6.
7
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8
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