Center for Alcohol and Addiction Studies, Brown University, Box G-S121-5, Providence, RI 02912, USA.
Nicotine Tob Res. 2010 Apr;12(4):381-9. doi: 10.1093/ntr/ntq014. Epub 2010 Feb 18.
Individual differences in psychopathology and personality may associate with dependence on smoking for specific motivational reasons. However, the associations among psychopathology, personality, and smoking dependence and motives have not been examined simultaneously in studies to date, leaving it unclear whether specific patterns of affective and behavioral functioning are associated with specific aspects of smoking dependence.
The present study examined these associations in 296 current smokers aged 35-43 years. Smoking dependence and motives were assessed with structured interview, the Fagerström Test for Nicotine Dependence, and the Wisconsin Inventory of Smoking Dependence Motives.
Regardless of the measure of smoking dependence tested, a lifetime history of major depression and high levels of trait stress reaction were consistently related to greater current smoking dependence severity. Substance dependence showed significant associations with some measures of smoking dependence but had relatively few effects when entered in models along with depression history and trait stress reaction. In multivariate models, alcohol dependence and conduct disorder history did not show unique significant associations with smoking dependence nor did trait aggression, alienation, control, or harm avoidance.
Results indicate little specificity in the associations of particular psychiatric diagnoses or personality traits with specific self-reported facets of smoking dependence. It appears that a general vulnerability to depression and negative emotions is the most robust indicator of vulnerability to high levels of self-reported smoking dependence, regardless of which dimensions of smoking dependence are analyzed.
精神病理学和人格的个体差异可能与出于特定动机依赖吸烟有关。然而,迄今为止的研究并未同时检查精神病理学、人格与吸烟依赖和动机之间的关联,因此不清楚特定的情感和行为功能模式是否与吸烟依赖的特定方面有关。
本研究在 296 名年龄在 35-43 岁的当前吸烟者中检查了这些关联。吸烟依赖和动机通过结构化访谈、尼古丁依赖 Fagerström 测试和威斯康星州吸烟依赖动机量表进行评估。
无论测试的吸烟依赖衡量标准如何,终生的重度抑郁症病史和高水平的特质压力反应与当前吸烟依赖严重程度呈持续相关。物质依赖与某些吸烟依赖衡量标准有显著关联,但当与抑郁病史和特质压力反应一起纳入模型时,其影响相对较小。在多元模型中,酒精依赖和品行障碍病史与吸烟依赖没有独特的显著关联,特质攻击性、疏离感、控制力或回避伤害也没有。
结果表明,特定精神科诊断或人格特质与吸烟依赖的特定自我报告方面之间的关联没有特异性。似乎对抑郁和负面情绪的普遍易感性是自我报告吸烟依赖水平较高的最有力指标,无论分析吸烟依赖的哪个维度。