Department of Radiologyand, University of Michigan Health System, Ann Arbor, USA.
AJNR Am J Neuroradiol. 2010 Apr;31(4):626-7. doi: 10.3174/ajnr.A2054. Epub 2010 Feb 18.
Cetuximab, a recombinant chimeric monoclonal antibody, has been successfully used in the treatment of the head and neck and colorectal cancers. We present a review of its mechanism of action, indications, side effects and economic issues, accompanied by a clinical example from our institution.
西妥昔单抗是一种重组嵌合单克隆抗体,已成功用于头颈部和结直肠癌的治疗。我们对其作用机制、适应证、副作用和经济问题进行了综述,并结合我院的 1 例临床病例进行了介绍。