Corbin Glenn S, Bennett Linda, Espejo Louis, Carducci Suzanne, Sacco Andrew, Hannigan Robert, Schatz Stuart
Wyomissing Optometric Center, Wyomissing, PA, USA.
Clin Ophthalmol. 2010 Feb 2;4:47-57. doi: 10.2147/opth.s7498.
Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE((R)) RepleniSH((R)) Multi-Purpose Disinfecting Solution (MPDS).
This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE((R)) Multi-Purpose Solution (MPS) Easy Rub((R)) or ReNu MultiPlus((R)) MPS. The test solution (OPTI-FREE((R)) RepleniSH((R)) MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit.
The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).
The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE((R)) MPS Easy Rub((R)) or ReNu MultiPlus((R)) MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.
证明使用竞争性多功能护理液的成功软性隐形眼镜佩戴者在使用OPTI-FREE((R)) RepleniSH((R))多功能消毒护理液（MPDS）后舒适度得到改善。
这项为期30天的多中心开放标签研究招募了109名符合条件的软性隐形眼镜佩戴者，他们使用COMPLETE((R))多功能护理液（MPS）易擦型((R))或ReNu MultiPlus((R)) MPS。发放测试护理液（OPTI-FREE((R)) RepleniSH((R)) MPDS）以替代其常用护理液。受试者使用李克特式问题评估他们对常用护理液（基线）和测试护理液（第30天）体验。每次就诊时记录隐形眼镜视力和生物显微镜检查结果。
测试护理液在滴入舒适度（P = 0.02）、一天结束时的舒适度（P < 0.0001）、清晰视力（P < 0.0001）和总体满意度（P < 0.001）方面有统计学显著改善。受试者报告测试护理液比他们之前的护理液更有效地提升了整体佩戴隐形眼镜的体验（P < 0.0001），并且他们在研究结束后会继续使用测试护理液（P < 0.0001）。
与COMPLETE((R)) MPS易擦型((R))或ReNu MultiPlus((R)) MPS相比，测试护理液在成功的隐形眼镜佩戴者中能有效改善舒适度和整体隐形眼镜体验。这些结果表明，即使是成功的隐形眼镜佩戴者，更换隐形眼镜护理液也可能改善舒适度和整体佩戴体验。
