对甲磺酰胺选择性脱保护为胺。
Selective deprotection of methanesulfonamides to amines.
机构信息
Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259-B-59 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.
出版信息
Org Lett. 2010 Mar 19;12(6):1228-30. doi: 10.1021/ol100086j.
PMID:20170144
Abstract
Methanesulfonamides were deprotected to their parent amines via deprotonation and oxygenation with O(2) (g), even in the presence of other traditional sulfonamides.
摘要
甲磺酰胺基被脱保护成相应的伯胺，通过与 O(2)（g）去质子化和氧化，即使在存在其它传统的磺胺的情况下也是如此。
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